Evidence mapPaperPMID 40569563Full record

ArticleEndocrine2025

Gestational diabetes mellitus subtypes according to oral glucose tolerance test and pregnancy outcomes.

Kleoniki I Athanasiadou, Stavroula A Paschou, Georgios Markozannes, Vasiliki Vasileiou, Fotini Kanouta, Marina Mitropoulou, Panagiotis Antsaklis, Mariana Theodora, Theodora Psaltopoulou, George Daskalakis and 2 more

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Article in Endocrine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

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4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Kleoniki I AthanasiadouEndocrine Unit and Diabetes Centre, Department of Clinical Therapeutics, Alexandra Hospital, School of Medicine, National and Kapodistrian University of Athens, Athens, Greece.ORCID 0000-0002-0811-8156
Stavroula A PaschouEndocrine Unit and Diabetes Centre, Department of Clinical Therapeutics, Alexandra Hospital, School of Medicine, National and Kapodistrian University of Athens, Athens, Greece. spaschou@med.uoa.gr.ORCID 0000-0002-0651-1376
Georgios MarkozannesDepartment of Hygiene and Epidemiology, School of Medicine, University of Ioannina, University Campus, Ioannina, Greece.
Vasiliki VasileiouDepartment of Endocrinology and Diabetes Centre, Alexandra Hospital, Athens, Greece.
Fotini KanoutaDepartment of Endocrinology and Diabetes Centre, Alexandra Hospital, Athens, Greece.
Marina MitropoulouDepartment of Endocrinology and Diabetes Centre, Alexandra Hospital, Athens, Greece.
Panagiotis Antsaklis1st Department of Obstetrics and Gynecology, Alexandra Hospital, National and Kapodistrian University of Athens, Athens, Greece.
Mariana Theodora1st Department of Obstetrics and Gynecology, Alexandra Hospital, National and Kapodistrian University of Athens, Athens, Greece.
Theodora PsaltopoulouEndocrine Unit and Diabetes Centre, Department of Clinical Therapeutics, Alexandra Hospital, School of Medicine, National and Kapodistrian University of Athens, Athens, Greece.
George Daskalakis1st Department of Obstetrics and Gynecology, Alexandra Hospital, National and Kapodistrian University of Athens, Athens, Greece.
Dimitrios G GoulisUnit of Reproductive Endocrinology, 1st Department of Obstetrics and Gynaecology, Medical School, Aristotle University of Thessaloniki, Thessaloniki, Greece.ORCID 0000-0002-5005-1995
Eleni AnastasiouDepartment of Endocrinology and Diabetes Centre, Alexandra Hospital, Athens, Greece.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo determine whether the abnormal glucose concentrations at various oral glucose tolerance test (OGTT) time points are associated with adverse perinatal outcomes in pregnancies complicated by gestational diabetes mellitus (GDM).

methodsA retrospective study included 257 pregnant women with GDM (IADPSG criteria) who delivered between 2020-2023 at a tertiary hospital. Women were classified based on their OGTT results: isolated fasting hyperglycemia (group A), isolated post-load hyperglycemia (group B), and combined hyperglycemia (group C). Multivariable linear and logistic regression analyses were performed.

resultsMost women had fasting hyperglycemia (54.1%), followed by isolated post-load hyperglycemia (29.2%), and combined hyperglycemia (16.7%). In the univariate analysis, women in Groups A and C had higher BMI before pregnancy (29.0 [7.6] kg/m

conclusionThe GDM subtypes identified through the OGTT were related to distinct metabolic phenotypes and pregnancy outcomes, indicating the presence of heterogeneity in GDM. Future studies are required to confirm these findings and explore whether the OGTT could be used to guide individualized GDM treatment.

Indexed as

Diabetes, GestationalHyperglycemiaPregnancy OutcomeAdultBirth WeightBlood GlucoseFemaleGlucose Tolerance TestHumansInfant, NewbornPregnancyRetrospective StudiesBlood GlucoseGDM subtypesGestational diabetes mellitusHeterogeneityOGTTPregnancy

Identifiers

PMID40569563
PMCPMC12464073

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.