Evidence map›Paper›PMID 40571559›Full record

Trial reportNeuropsychological rehabilitation2026

Measurement of cross-language and cross-domain generalization following semantic feature-based anomia treatment in bilingual aphasia.

Marissa Russell-Meill, Erin Carpenter, Manuel J Marte, Michael Scimeca, Claudia Peñaloza, Swathi Kiran

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Neuropsychological rehabilitation, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Marissa Russell-MeillCenter for Brain Recovery, Boston University, Boston, MA, USA.ORCID 0000-0002-9610-6832
Erin CarpenterCenter for Brain Recovery, Boston University, Boston, MA, USA.ORCID 0000-0002-7958-6803
Manuel J MarteCenter for Brain Recovery, Boston University, Boston, MA, USA.ORCID 0000-0002-1837-601X
Michael ScimecaCenter for Brain Recovery, Boston University, Boston, MA, USA.ORCID 0000-0002-1683-7767
Claudia PeñalozaDepartment of Cognition, Development and Educational Psychology, Faculty of Psychology, University of Barcelona, Barcelona, Spain.ORCID 0000-0003-1200-5936
Swathi KiranCenter for Brain Recovery, Boston University, Boston, MA, USA.ORCID 0000-0003-1586-8913

Funding

Advanced Research Training in Communication Sciences and DisordersT32DC013017 · NIDCD · BOSTON UNIVERSITY (CHARLES RIVER CAMPUS) · PI Cara E. Stepp · 2016 to 2026
$4.9M
Predicting rehabilitation outcomes in bilingual aphasia using computational modelingU01DC014922 · NIDCD · BOSTON UNIVERSITY (CHARLES RIVER CAMPUS) · PI KIRAN, SWATHI, MIIKKULAINEN, RISTO · 2016 to 2020
$3.5M
NIDCD NIH HHS T32 DC013017NIDCD NIH HHS U01 DC014922
6 · The paper itself

Abstract

Semantic feature-based treatment (SFT), which engages the semantic network by repeatedly targeting retrieval of conceptual features to improve lexical-semantic access, has shown promise for facilitating generalization in aphasia rehabilitation. However, its capacity to drive broad improvement across cognitive-linguistic domains in bilinguals with aphasia (BWA) remains unclear. This study examined generalization effects (i.e., direct transfer, near transfer, and far transfer) following SFT in 48 Spanish-English BWA who took part in a randomized controlled trial. Participants received 40 h of SFT targeting word retrieval, with generalization assessed across three domains: naming of untrained items (direct transfer), semantic processing (near transfer), as well as global language ability and nonverbal abstract reasoning (far transfer). Results showed (i) robust improvements for trained and untrained naming targets, demonstrating direct transfer, (ii) near transfer effects for select semantic processing tasks, and (iii) far transfer limited to overall language function, with no gains in domain-general cognition. Notably, treatment benefits extended across languages, demonstrating cross-language generalization to multiple domains of language processing. Findings highlight SFT's capacity to drive comprehensive language recovery in BWA, revealing broad generalization effects across languages and linguistic domains. Such effects underscore the importance of systematically examining generalization patterns to optimize rehabilitation outcomes.

Indexed as

AnomiaAphasiaGeneralization, PsychologicalLanguage TherapyMultilingualismOutcome Assessment, Health CareSemanticsTransfer, PsychologyAdultAgedFemaleHumansMaleMiddle Agedaphasia rehabilitationBilingual aphasiacross-language generalizationfar transfernear transfertreatment outcomes

Identifiers

PMID40571559
PMCPMC12355654

What Socratic holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.