Evidence map›Paper›PMID 40571671›Full record

SynthesisRenal failure2025

Suicide risk in patients undergoing hemodialysis: a systematic review and meta-analysis of prevalence.

Luigi Zerbinati, Federica Caccia, Federica Baciga, Martino Belvedere Murri, Pasquale Esposito, Rosangela Caruso, Ionut Nistor, Bjorn Meijers, Carlo Basile, Christian Combe and 4 more

Abstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Renal failure, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Clinical and psychological changes associated with music listening in haemodialysis patients: A prospective study.The South African journal of psychiatry : SAJP : the journal of the Society of Psychiatrists of South Africa · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Luigi ZerbinatiInstitute of Psychiatry, Department of Biomedical and Specialty Surgical Sciences, University of Ferrara, Ferrara, Italy.ORCID 0000-0001-6821-1005
Federica CacciaDepartment of Medicine, University of Verona, Verona, Italy.ORCID 0009-0003-3179-9193
Federica BacigaDepartment of Medicine, University of Verona, Verona, Italy.ORCID 0009-0002-8866-3660
Martino Belvedere MurriInstitute of Psychiatry, Department of Biomedical and Specialty Surgical Sciences, University of Ferrara, Ferrara, Italy.ORCID 0000-0002-7262-3528
Pasquale EspositoDepartment of Internal Medicine, Division of Nephrology, Dialysis and Transplantation, University of Genoa and IRCCS Ospedale Policlinico San Martino, Genoa, Italy.ORCID 0000-0002-0834-5586
Rosangela CarusoInstitute of Psychiatry, Department of Biomedical and Specialty Surgical Sciences, University of Ferrara, Ferrara, Italy.ORCID 0000-0002-6662-2270
Ionut NistorNephrology Department, University of Medicine and Pharmacy, Grigore T.Popa", Iași, Romania.ORCID 0009-0003-1659-7294
Bjorn MeijersNephrology Unit, University Hospitals Leuven, Leuven, Belgium.ORCID 0000-0002-2846-2026
Carlo BasileSezione di Nefrologia, Associazione Nefrologica Gabriella Sebastio, Martina Franca, Italy.ORCID 0000-0001-8152-5471
Christian CombeUniversity of Bordeaux, INSERM, Bordeaux Public Health, Bordeaux, France.ORCID 0000-0002-0360-573X
Luigi GrassiInstitute of Psychiatry, Department of Biomedical and Specialty Surgical Sciences, University of Ferrara, Ferrara, Italy.ORCID 0000-0002-1050-4494
Alessandro MantovaniSection of Endocrinology, Diabetes and Metabolism, Department of Medicine, University and Azienda Ospedaliera Universitaria Integrata of Verona, Verona, Italy.ORCID 0000-0002-7271-6329
Yuri BattagliaDepartment of Medicine, University of Verona, Verona, Italy.ORCID 0000-0003-3947-1814
EuDial Working Group of ERA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundKidney failure is strongly associated with psychological disorders, including anxiety, depression, and suicidal ideation. However, the prevalence of suicide risk in patients undergoing dialysis has not been fully established.

methodsWe performed a systematic review and meta-analysis aimed at assessing the prevalence of suicide risk in adult patients on dialysis and any correlation with demographic and clinical parameters.

resultsTwelve unique cross-sectional studies involving 1259 adult patients on dialysis were included. All patients were receiving hemodialysis treatment. In univariate meta-regression analysis, no significant effect of age, sex, and percentage of patients with diabetes mellitus on the prevalence of suicide risk was found. Overall, the prevalence of suicide risk was 20.6%. It varied widely, ranging from 4.0% to 57.3%, depending on the tools used (i.e. clinical interviews or self-report questionnaires). Among studies with more or less than 40% of patients on dialysis with anxiety and depression, the prevalence of suicide risk was very similar (21.2% vs 20.4%, respectively). The prevalence of suicide risk was more than double in lower-income than in higher-income countries (33.5% vs 15.3%, respectively).

conclusionsThe present systematic review and meta-analysis is a pioneering effort to identify the prevalence of suicide risk in patients on dialysis. It revealed a significant prevalence of suicide risk among hemodialysis patients, with a rate notably higher than that observed in the general population. This elevated risk is influenced by a complex combination of biological, psychological, and socio-economic factors.

Indexed as

Kidney Failure, ChronicRenal DialysisSuicideAnxietyCross-Sectional StudiesDepressionHumansPrevalenceRisk FactorsSuicidal IdeationanxietydepressionDialysiskidney failureMINIsuicide

Identifiers

PMID40571671
PMCPMC12203703

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.