Evidence mapPaperPMID 40573113Full record

ReviewNutrients2025

Dos and Don'ts in Kidney Nutrition: Practical Considerations of a Panel of Experts on Protein Restriction and Plant-Based Diets for Patients Living with Chronic Kidney Disease.

Massimo Torreggiani, Carla Maria Avesani, Barbara Contzen, Adamasco Cupisti, Sylwia Czaja-Stolc, Claudia D'Alessandro, Liliana Garneata, Abril Gutiérrez, Françoise Lippi, Carmen Antonia Mocanu and 3 more

Abstract readReview
In one paragraph

Review in Nutrients, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Trial
  2. Article
  3. Review
  4. Low Dietary Iodine Intake and Sex-Specific Mortality in Kidney Transplant Recipients.Clinical journal of the American Society of Nephrology : CJASN · 2026
    Observational
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Massimo TorreggianiNéphrologie et Dialyse, Centre Hospitalier Le Mans, 72037 Le Mans, France.ORCID 0000-0002-5561-948X
Carla Maria AvesaniDivision of Renal Medicine, Baxter Novum, Department of Clinical Science Intervention and Technology, Karolinska Institutet, 14186 Stockholm, Sweden.ORCID 0000-0002-4458-8358
Barbara ContzenNephroLogik-Ernährungstherapie bei Chronischer Niereninsuffizienz, 51465 Bergisch Gladbach, Germany.
Adamasco CupistiDivision of Nephrology, Department of Clinical and Experimental Medicine, University of Pisa, 56126 Pisa, Italy.ORCID 0000-0002-8995-936X
Sylwia Czaja-StolcDepartment of Clinical Nutrition and Dietetics, Faculty of Health Sciences, Medical University of Gdansk, 80-211 Gdansk, Poland.
Claudia D'AlessandroDivision of Nephrology, Department of Clinical and Experimental Medicine, University of Pisa, 56126 Pisa, Italy.ORCID 0000-0003-2313-5461
Liliana GarneataDepartment of Internal Medicine and Nephrology, Carol Davila University of Medicine and Pharmacy, 050474 Bucharest, Romania.
Abril GutiérrezSociedad Mexicana de Etudios en Ciencias de la Salud, Mexico City 06760, Mexico.
Françoise LippiNéphrologie et Dialyse, Centre Hospitalier Le Mans, 72037 Le Mans, France.
Carmen Antonia MocanuDepartment of Internal Medicine and Nephrology, Carol Davila University of Medicine and Pharmacy, 050474 Bucharest, Romania.
Alice SabatinoDivision of Renal Medicine, Baxter Novum, Department of Clinical Science Intervention and Technology, Karolinska Institutet, 14186 Stockholm, Sweden.ORCID 0000-0003-2098-7597
Giorgina Barbara PiccoliNéphrologie et Dialyse, Centre Hospitalier Le Mans, 72037 Le Mans, France.ORCID 0000-0002-2632-4009
European Renal Nutrition (ERN) Working Group of the European Renal Association (ERA)

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Dietary management is a pillar of chronic kidney disease (CKD) treatment. While some rules are the same as dietary prescriptions for the general population and those suffering from other chronic diseases (energy intake, salt intake, avoidance of ultra-processed food and limited intake of animal fats), in non-dialysis-dependent patients living with CKD, the specific focus is on protein intake. Low-protein diets (LPDs) and supplemented very low protein diets (sVLPDs) have been successfully employed to decrease the symptoms of people living with non-dialysis-dependent CKD, delay the progression of the disease and retard the need for dialysis. Randomized clinical trials have yielded conflicting results on efficacy, resulting in conflicting guidelines. Concerns about the risk of malnutrition (specifically when the main source of proteins is plant-derived), electrolyte imbalances, and energy intake, and the idea that adherence is difficult, jeopardize the use and wide application of LPDs and sVLPDs. That dietary management focuses mainly on nutrients while dietary quality occupies second place is also an erroneous concept that requires discussion. In September 2023, a group of experts composed of nephrologists and dieticians gathered in Frankfurt, Germany, to try to reconcile the different guideline indications and address most of the common doubts of final dispatchers to increase the prescription of "renal diets" and improve people living with CKD's adherence to them.

Indexed as

Diet, Protein-RestrictedDiet, VegetarianKidneyRenal Insufficiency, ChronicDietary ProteinsDiet, Plant-BasedHumansNutritional StatusPractice Guidelines as TopicDietary Proteinseducationelderly patientsketoanalogueslow-protein dietsprotein intakeultra-processed food

Identifiers

PMID40573113
PMCPMC12195896

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.