Evidence map›Paper›PMID 40573199›Full record

ArticlePharmaceuticals (Basel, Switzerland)2025

New Nitrogen-, Oxygen-, and Sulfur-Containing Heterocyclic Compounds as Anti-Colon Cancer Agents: Synthesis, Multitargeted Evaluations, Molecular Docking Simulations and ADMET Predictions.

Nahed Nasser Eid El-Sayed, Najeh Krayem, Hamed Ahmed Derbala, Shimaa Kamal, Syde Nasir Abbas Bukhari, Mohamed K El-Ashrey, Zainab M Almarhoon, Seham Soliman Alterary, Abir Ben Bacha

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Pharmaceuticals (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Triazole-(RSC advances · 2026
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Nahed Nasser Eid El-SayedEgyptian Drug Authority, 51 Wezaret El-Zerra St., Giza 35521, Egypt.
Najeh KrayemLaboratoire de Biochimie et de Génie Enzymatique des Lipases, ENIS, Université de Sfax, Route de Soukra 3038, Sfax BP 1173, Tunisia.
Hamed Ahmed DerbalaChemistry Department, Faculty of Science, Ain Shams University, Abbassia, Cairo 11566, Egypt.
Shimaa KamalChemistry Department, Faculty of Science, Ain Shams University, Abbassia, Cairo 11566, Egypt.
Syde Nasir Abbas BukhariDepartment of Pharmaceutical Chemistry, College of Pharmacy, Jouf University, Sakaka 72388, Saudi Arabia.ORCID 0000-0001-8125-7972
Mohamed K El-AshreyPharmaceutical Chemistry Department, Faculty of Pharmacy, Cairo University, Kasr Elini St., Cairo 11562, Egypt.ORCID 0000-0002-3548-3888
Zainab M AlmarhoonDepartment of Chemistry, College of Science, King Saud University, P.O. Box 2455, Riyadh 11451, Saudi Arabia.ORCID 0000-0001-8196-2612
Seham Soliman AlteraryDepartment of Chemistry, College of Science, King Saud University, P.O. Box 2455, Riyadh 11451, Saudi Arabia.
Abir Ben BachaBiochemistry Department, College of Sciences, King Saud University, P.O. Box 22452, Riyadh 11495, Saudi Arabia.ORCID 0000-0001-6372-7483

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

ADMETapoptosiscolorectal cancerheterocyclic compoundsmultitarget-directed ligandsoxidative stressWarburg effect

Identifiers

PMID40573199
PMCPMC12196476

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.