Evidence map›Paper›PMID 40573474›Full record

ReviewSensors (Basel, Switzerland)2025

Recent Advances in Aptamer-Based Point-of-Care Testing.

Senlin Luo, Xiaotian Zhang, Yuzhuo Zhang, Xiaofeng Qu, Qiru Sun, Tianhuan Peng, Quan Yuan

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Sensors (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Senlin LuoDepartment of Pediatrics, The Second Xiangya Hospital, Central South University, Changsha 410011, China.
Xiaotian ZhangMolecular Science and Biomedicine Laboratory (MBL), State Key Laboratory of Chemo and Biosensing, College of Biology, College of Chemistry and Chemical Engineering, Aptamer Engineering Center of Hunan Province, Hunan University, Changsha 410082, China.
Yuzhuo ZhangMolecular Science and Biomedicine Laboratory (MBL), State Key Laboratory of Chemo and Biosensing, College of Biology, College of Chemistry and Chemical Engineering, Aptamer Engineering Center of Hunan Province, Hunan University, Changsha 410082, China.
Xiaofeng QuMolecular Science and Biomedicine Laboratory (MBL), State Key Laboratory of Chemo and Biosensing, College of Biology, College of Chemistry and Chemical Engineering, Aptamer Engineering Center of Hunan Province, Hunan University, Changsha 410082, China.
Qiru SunMolecular Science and Biomedicine Laboratory (MBL), State Key Laboratory of Chemo and Biosensing, College of Biology, College of Chemistry and Chemical Engineering, Aptamer Engineering Center of Hunan Province, Hunan University, Changsha 410082, China.
Tianhuan PengMolecular Science and Biomedicine Laboratory (MBL), State Key Laboratory of Chemo and Biosensing, College of Biology, College of Chemistry and Chemical Engineering, Aptamer Engineering Center of Hunan Province, Hunan University, Changsha 410082, China.ORCID 0000-0002-2229-2687
Quan YuanMolecular Science and Biomedicine Laboratory (MBL), State Key Laboratory of Chemo and Biosensing, College of Biology, College of Chemistry and Chemical Engineering, Aptamer Engineering Center of Hunan Province, Hunan University, Changsha 410082, China.

Funding

Guangdong Basic and Applied Basic Research Foundation 2022A1515220118National Key Research and Development Program of China 2020YFA0210800National Natural Science Foundation of China 2210702
6 · The paper itself

Abstract

Aptamers refer to a class of oligonucleotide probes that have demonstrated remarkable capabilities beyond mere genetic coding, including the unique ability to recognize and selectively bind to specific molecular targets. Numerous advantages, including accessibility for targeting a diverse array of molecules and compatibility with different signal amplification and transduction elements, underscore the application of aptamers for delivering rapid and accurate diagnostic tests at the point of care. This review provides a comprehensive summary of the recent advances in aptamer-based point-of-care testing, especially highlighting the innovative applications of aptamers in colorimetric sensors, lateral flow assays, fluorescent biosensors, and electrochemical biosensors. Additionally, current challenges in this burgeoning field and forward-looking perspectives for aptamer-based point-of-care testing are discussed.

Indexed as

Aptamers, NucleotideBiosensing TechniquesPoint-of-Care SystemsPoint-of-Care TestingColorimetryElectrochemical TechniquesHumansAptamers, Nucleotideaptamerscolorimetric sensorselectrochemical biosensingfluorescent assaypoint-of-care diagnosis

Identifiers

PMID40573474
PMCPMC12196720

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.