Evidence map›Paper›PMID 40574008›Full record

ReviewPharmaceutics2025

Recent Insights into the Potential and Challenges of Sericin as a Drug Delivery Platform for Multiple Biomedical Applications.

Qisan Ma, Saniya Salathia, Maria Rosa Gigliobianco, Cristina Casadidio, Piera Di Martino, Roberta Censi

Abstract readReview
In one paragraph

Review in Pharmaceutics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Qisan MaChIP Chemistry Interdisciplinary Project Research Centre, School of Pharmacy, University of Camerino, Via Madonna delle Carceri, 62032 Camerino, MC, Italy.
Saniya SalathiaChIP Chemistry Interdisciplinary Project Research Centre, School of Pharmacy, University of Camerino, Via Madonna delle Carceri, 62032 Camerino, MC, Italy.ORCID 0000-0001-5145-7236
Maria Rosa GigliobiancoDepartment of Pharmacy, "G. D'Annunzio" of Chieti and Pescara University, Via dei Vestini 1, 66100 Chieti, CH, Italy.
Cristina CasadidioChIP Chemistry Interdisciplinary Project Research Centre, School of Pharmacy, University of Camerino, Via Madonna delle Carceri, 62032 Camerino, MC, Italy.ORCID 0000-0002-3925-7087
Piera Di MartinoDepartment of Pharmacy, "G. D'Annunzio" of Chieti and Pescara University, Via dei Vestini 1, 66100 Chieti, CH, Italy.ORCID 0000-0002-7657-3556
Roberta CensiChIP Chemistry Interdisciplinary Project Research Centre, School of Pharmacy, University of Camerino, Via Madonna delle Carceri, 62032 Camerino, MC, Italy.

Funding

This work was financially supported by the National Recovery and Resilience Plan (NRRP), Mis-sion 4, Component 2, Investment 1.1, Call for tender No. 104 published on 2.2.2022 by the Italian Ministry of University and Research (MUR), funded by the Europea PROJECT ID: 20222W7P7S - CUP: J53D23007270006. Grant Assignment Decree No. n. 1064 adopted on 18/07/2023 by the Italian Ministry of Ministry of University and Research (MUR).
6 · The paper itself

Abstract

Sericin, a glycoprotein derived from silk cocoons, has gained significant attention as a versatile biomaterial for drug delivery due to its biocompatibility, biodegradability, and amphipathic nature. This review explores recent advancements in sericin-based drug delivery systems across three key therapeutic domains: antimicrobial applications, anticancer treatments, and neurodegenerative diseases. Various fabrication techniques, including nanoparticles, hydrogels, and microneedles, have been investigated to optimize drug encapsulation, targeted release, and bioavailability. While sericin holds great promise for overcoming challenges associated with synthetic polymers, issues such as molecular variability, formulation stability, and regulatory considerations remain critical hurdles. Future research should focus on optimizing sericin extraction methods, enhancing structural stability, and integrating it with cutting-edge biomedical technologies to maximize its therapeutic efficacy.

Indexed as

biomaterialsbiopolymer engineeringcontrolled releasenanocarrierstargeted therapy

Identifiers

PMID40574008
PMCPMC12195889

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.