Evidence map›Paper›PMID 40574533›Full record

ReviewLipids2025

Recognizing the Health Benefits of Plant-Sourced Omega-3 Stearidonic Acid: Exploring Its Complementary Role to Preformed EPA/DHA.

Ella J Baker, Greg Cumberford, Patrick Hanaway

Abstract readReview
In one paragraph

Review in Lipids, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Ella J BakerSchool of Human Development and Health, Faculty of Medicine, University of Southampton, Southampton, UK.ORCID 0000-0003-1008-5506
Greg CumberfordNatures Crops International, Kensington, Prince Edward Island, Canada.
Patrick HanawayFamily to Family, Weaverville, North Carolina, USA.

Funding

NIHR Southampton Biomedical Research Centre
6 · The paper itself

Abstract

Long-chain (LC) omega-3 polyunsaturated fatty acids (PUFAs) like eicosapentaenoic acid (EPA), and docosahexaenoic acid (DHA) are crucial for optimal development, healthy aging, and disease management. Traditionally sourced from fatty fish, these omega-3 PUFAs face sustainability challenges, prompting increased exploration of plant-based alternatives, such as stearidonic acid (SDA). Recent studies highlight the efficient conversion of SDA to EPA, meaning that SDA may offer similar health benefits to EPA, including immune, joint, cognitive, and gut microbiome modulation (with distinct SDA-derived metabolites). This mini-review explores new research on SDA and its potential to deliver human health benefits. SDA-rich oils, notably Buglossoides arvensis oil (RBO; also known as Ahiflower oil) provide an eco-friendly, sustainable alternative to fish-derived omega-3 PUFAs. As concerns about marine omega-3 PUFA sources grow, SDA-rich oils present a viable option for clinicians and consumers seeking effective omega-3 PUFA supplementation.

Indexed as

Docosahexaenoic AcidsEicosapentaenoic AcidFatty Acids, Omega-3AnimalsDietary SupplementsHumansPlant OilsDocosahexaenoic AcidsEicosapentaenoic AcidFatty Acids, Omega-3Plant Oilsstearidonic acidAhiflower oildocosahexaenoic acideicosapentaenoic acidomega‐3stearidonic acidsustainability

Identifiers

PMID40574533
PMCPMC12611454

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.