ReviewPrecision chemistry2025
Multiplex Detection of Biomarkers Empowered by Nanomaterials.
Review in Precision chemistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
7 citing papers in PubMed.
- Strategies for Multiplexing Plasmonic Biosensing.Sensors (Basel, Switzerland) · 2026Review
- Advances in nanomaterial-enhanced immunosensors for ultra-sensitive tumor marker detection: Enabling early cancer diagnostics.Frontiers in chemistry · 2026Review
- Nanobiosensors for Rheumatoid Arthritis Biomarkers: Advances and Clinical Translational Potential.International journal of nanomedicine · 2026Review
- Precision Chemistry in Precision Diagnostics.Precision chemistry · 2025Article
- Potential-Resolved Electrochemiluminescence and Its Application in Disease Biomarker Detection.Biosensors · 2025Review
- AI-Enhanced Electrochemical Sensing Systems: A Paradigm Shift for Intelligent Food Safety Monitoring.Biosensors · 2025Review
- Multianalyte nano-biosensor diagnostics: advances through microfluidic and AI integration.Frontiers in bioengineering and biotechnology · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Biomarkers, including proteins, nucleic acids, and metabolites, are the molecules that can provide insightful information about biological processes and pathological developments. Identification and quantification of biomarkers are highly beneficial for disease diagnosis, progression monitoring, and treatment supervision. However, disease development often involves the complex interplay of molecular networks that limits the utility of individual biomarkers in reaching reliable diagnostic and therapeutic decisions. Thus, recent developments of bioassays have turned the focus to analysis of a collection of biomarkers simultaneously, aiming to improve precision in diagnosis. To achieve the demanded throughput in multiplex detection while keeping the excellent analytical performance in speed, sensitivity, and selectivity, nanomaterials stand out to be the proper enabling tools, with their unique but highly diversified physical and chemical properties and the much advanced synthesis strategies. Herein, this review highlights the recent (2020-2024) developments in the nanomaterial-enabled, optical multiplex sensing techniques. Four key approaches to achieve multiplexity were discussed: spatial coding, signal coding, biocarriers, and data deconvolution using machine learning. We believe these advancements have driven forward the applications of multiplex detection in clinical settings by improving the throughput of biomarker analysis.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.