Evidence map›Paper›PMID 40575130›Full record

ReviewPatterns (New York, N.Y.)2025

How quantum computing can enhance biomarker discovery.

Frederik F Flöther, Daniel Blankenberg, Maria Demidik, Karl Jansen, Raga Krishnakumar, Rajiv Krishnakumar, Nouamane Laanait, Laxmi Parida, Carl Y Saab, Filippo Utro

Abstract readReview
In one paragraph

Review in Patterns (New York, N.Y.), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Population health management of human phenotype ontology.Frontiers in artificial intelligence · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Frederik F FlötherQuantumBasel, Schorenweg 44b, Arlesheim 4144, Switzerland.
Daniel BlankenbergCleveland Clinic, 9500 Euclid Avenue, Cleveland, OH 44195, USA.
Maria DemidikDeutsches Elektronen-Synchrotron DESY, Platanenallee 6, Zeuthen 15738, Germany.
Karl JansenDeutsches Elektronen-Synchrotron DESY, Platanenallee 6, Zeuthen 15738, Germany.
Raga KrishnakumarSandia National Laboratories, 7011 East Avenue, Livermore, CA 94550, USA.
Rajiv KrishnakumarQuantumBasel, Schorenweg 44b, Arlesheim 4144, Switzerland.
Nouamane LaanaitElevance Health, 740 W Peachtree St. NW, Atlanta, GA 30308, USA.
Laxmi ParidaIBM Thomas J. Watson Research Center, 1101 Kitchawan Road, Yorktown Heights, NY 10598, USA.
Carl Y SaabCleveland Clinic, 9500 Euclid Avenue, Cleveland, OH 44195, USA.
Filippo UtroIBM Thomas J. Watson Research Center, 1101 Kitchawan Road, Yorktown Heights, NY 10598, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Biomarkers play a central role in medicine's gradual progress toward proactive, personalized precision diagnostics and interventions. However, finding biomarkers that provide very early indicators of a change in health status, for example, for multifactorial diseases, has been challenging. The discovery of such biomarkers stands to benefit significantly from advanced information processing and means to detect complex correlations, which quantum computing offers. In this perspective, quantum algorithms, particularly in machine learning, are mapped to key applications in biomarker discovery. The opportunities and challenges associated with the algorithms and applications are discussed. The analysis is structured according to different data types-multidimensional, time series, and erroneous data-and covers key data modalities in healthcare-electronic health records, omics, and medical images. An outlook is provided concerning open research challenges.

Identifiers

PMID40575130
PMCPMC12191739

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.