ReviewCureus2025
Role of Pharmacology in Dentistry: A Review of Analgesics, Antibiotics, and Local Anesthetics.
Review in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Effect of pre-treatment systemic antibiotics on post-operative pain following single-visit root canal therapy in vital mandibular first premolars: A randomized controlled trial.Bioinformation · 2026Article
- Bridging the gap: a card-based pharmacology resource to support prescribing in undergraduate dental clinical training.Frontiers in medicine · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This review explores the essential role of pharmacology in dentistry, emphasizing the use of analgesics, antibiotics, and local anesthetics in managing pain, controlling infections, and ensuring procedural comfort. The integration of these pharmacological agents has significantly advanced dental care, allowing for more effective and patient-friendly treatments. Nonsteroidal anti-inflammatory drugs (NSAIDs) and acetaminophen serve as the primary analgesics, while opioids, despite their efficacy in severe cases, require careful prescribing due to their high risk of dependency and adverse effects. Antibiotics are indispensable for treating odontogenic infections and preventing systemic complications, yet their overuse has contributed to the global challenge of antimicrobial resistance, necessitating stringent antibiotic stewardship in dental practice. Local anesthetics, particularly lidocaine and articaine, have revolutionized pain-free dentistry, with advancements such as liposomal formulations, buffered anesthetics, and computer-assisted anesthesia enhancing their effectiveness and safety. Despite these innovations, challenges such as opioid dependency, antibiotic resistance, and individual variability in anesthetic response underscore the need for personalized pharmacotherapy. Emerging research in pharmacogenomics and novel drug delivery systems holds promise for optimizing treatment outcomes by tailoring pharmacological interventions to individual patient profiles. Future directions should focus on integrating precision medicine, improving antimicrobial strategies, and developing safer, more efficient anesthetic techniques. By incorporating evidence-based prescribing practices and adopting innovative pharmacological approaches, dentistry can continue to evolve toward safer, more effective, and patient-centered care.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.