ArticleCureus2025
A Simple Experimental Approach to Understanding the Formation of Advanced Glycation End Products.
Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionAdvanced glycation end products (AGEs) are non-enzymatically formed through reactions between sugars and proteins. Over the past decades, accumulating evidence has linked AGEs to the acceleration of aging and various pathological processes. Despite their biological significance, AGEs remain largely unrecognized by the general public. Therefore, new initiatives are needed to raise awareness of AGEs.
methodsAn AGE colorimetric sheet was developed. The glycation process of collagen with saccharides was analyzed using the sheet under various conditions, along with the physical properties of the protein.
resultsThe glycation process of collagen depended on time, dose, and temperature. Additionally, we identified a correlation between AGE levels and the mechanical toughness of the collagen matrix. Furthermore, commercially available beverages containing fructose significantly accelerated collagen glycation.
conclusionOur data demonstrate that the novel colorimetric sheet is a practical tool for assessing AGE formation without requiring specialized analytical instruments. This experimental system can enhance public health awareness, contributing to advances in preventive medicine and promoting healthy aging.
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Registered trials
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