Evidence mapPaperPMID 40575263Full record

ArticleFrontiers in endocrinology2025

Vitamin D deficiency and VDR

Addisu Melake, Misganaw Asmamaw Mengstie

Abstract read
In one paragraph

Article in Frontiers in endocrinology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Association of vitamin D receptorJournal of clinical tuberculosis and other mycobacterial diseases · 2026
    Article
  2. The Role of Vitamin D in Autoimmune Diseases.International journal of molecular sciences · 2026
    Review
  3. Recent Updates on Diabetes and Bone.International journal of molecular sciences · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Addisu MelakeDepartment of Medical Biochemistry, College of Health Science, Debre Tabor University, Debre Tabor, Ethiopia.
Misganaw Asmamaw MengstieDepartment of Medical Biochemistry, College of Health Science, Debre Tabor University, Debre Tabor, Ethiopia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Many studies have shown that vitamin D deficiency and vitamin D receptor TaqI gene polymorphisms are associated with susceptibility to diabetic nephropathy in various populations. The objective of this study was to determine the impact of vitamin D deficiency and vitamin D receptor Methods: A total of 210 participants, including 70 diabetic patients with nephropathy, 70 diabetic patients without nephropathy, and 70 healthy controls, participated in an age-and sex-matched hospital-based case-control study. Demographic and clinical data were assessed to determine the related risk factors. DNA was extracted from blood samples and subjected to polymerase chain reaction and agarose gel electrophoresis analysis to determine the Results: Vitamin D deficiency was detected in our investigation, and it was much more prevalent in diabetic nephropathy patients than type 2 diabetic patients and controls (OR = 5.05, 95% CL = 2.03-12.53; Conclusions: The findings point to a potential link between vitamin D deficiency and diabetic nephropathy complications. Moreover,

Indexed as

Diabetes Mellitus, Type 2Diabetic NephropathiesPolymorphism, GeneticReceptors, CalcitriolVitamin D DeficiencyAdultAgedCase-Control StudiesEthiopiaFemaleGenetic Predisposition to DiseaseGenotypeHumansMaleMiddle AgedRisk FactorsReceptors, CalcitriolVDR protein, humandiabetic nephropathyEthiopiaTaqItype 2 diabetes mellitusvitamin D deficiency

Identifiers

PMID40575263
PMCPMC12197910

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.