Evidence map›Paper›PMID 40575357›Full record

ReviewWorld journal of gastrointestinal pharmacology and therapeutics2025

Probiotics and prebiotics in the treatment of functional constipation in the elderly individuals.

Li Xu, Jian-Tang Guo, Jing Zhao, Ming-He Liu, Chen Mo

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in World journal of gastrointestinal pharmacology and therapeutics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Li XuDepartment of Gerontology, The Third Medical Center of PLA General Hospital, Beijing 100039, China.
Jian-Tang GuoDepartment of Gerontology, The Third Medical Center of PLA General Hospital, Beijing 100039, China.
Jing ZhaoDepartment of Gerontology, The Third Medical Center of PLA General Hospital, Beijing 100039, China.
Ming-He LiuDepartment of Gerontology, The Third Medical Center of PLA General Hospital, Beijing 100039, China.
Chen MoDepartment of Gerontology, The Third Medical Center of PLA General Hospital, Beijing 100039, China. mchen@sohu.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Functional constipation (FC) in elderly individuals is a significant health issue that adversely affects their quality of life, with recent studies indicating a close relationship between this condition and gut microbiota dysbiosis. This review aims to explore the role of the gut microbiota in FC in elderly individuals, analyze the mechanisms of the gut-brain axis, and evaluate the potential use of microecological agents, including probiotics and prebiotics, in modulating the gut microbiota and alleviating constipation symptoms. By integrating the latest research findings, this study seeks to provide new perspectives and intervention strategies for the management of FC in elderly individuals.

Indexed as

ElderlyFunctional constipationGut-brain axisGut microbiotaMicrobiota dysbiosisPrebioticProbiotics

Identifiers

PMID40575357
PMCPMC12188849

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.