Evidence map›Paper›PMID 40575783›Full record

ArticleFrontiers in pharmacology2025

The flexibility of SABRE, a new quantitative receptor function model, when fitting challenging concentration-effect data.

Barbara Olah, Vera Tarjanyi, Barbara Takacs, Edua Pluzsnyik, Gabor Viczjan, Ignac Ovari, Zoltan Szilvassy, Bela Juhasz, Judit Zsuga, Tamas Erdei and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in pharmacology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Barbara OlahDepartment of Orthodontics, Faculty of Dentistry, University of Debrecen, Debrecen, Hungary.
Vera TarjanyiUniversity of Debrecen, Doctoral School of Nutrition and Food Sciences, Debrecen, Hungary.
Barbara TakacsDepartment of Pharmacology and Pharmacotherapy, Faculty of Medicine, University of Debrecen, Debrecen, Hungary.
Edua PluzsnyikDepartment of Pharmacology and Pharmacotherapy, Faculty of Medicine, University of Debrecen, Debrecen, Hungary.
Gabor ViczjanDepartment of Pharmacology and Pharmacotherapy, Faculty of Medicine, University of Debrecen, Debrecen, Hungary.
Ignac OvariDepartment of Pharmacology and Pharmacotherapy, Faculty of Medicine, University of Debrecen, Debrecen, Hungary.
Zoltan SzilvassyDepartment of Pharmacology and Pharmacotherapy, Faculty of Medicine, University of Debrecen, Debrecen, Hungary.
Bela JuhaszDepartment of Pharmacology and Pharmacotherapy, Faculty of Medicine, University of Debrecen, Debrecen, Hungary.
Judit ZsugaDepartment of Psychiatry, Faculty of Medicine, University of Debrecen, Debrecen, Hungary.
Tamas ErdeiDepartment of Pharmacology and Pharmacotherapy, Faculty of Medicine, University of Debrecen, Debrecen, Hungary.
Rudolf GesztelyiDepartment of Pharmacology and Pharmacotherapy, Faculty of Medicine, University of Debrecen, Debrecen, Hungary.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The Signal Amplification, Binding affinity, and Receptor-activation Efficacy (SABRE) model is the most recent general and quantitative model of receptor function, which enables the determination of K

Indexed as

atriumcurve fittingfurchgott methodinotropyoperational modelSABRE model

Identifiers

PMID40575783
PMCPMC12198161

What Socratic holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.