Evidence mapPaperPMID 40576010Full record

ArticleGut microbes2025

Lactulose selectively stimulates members of the gut microbiota, as determined by multi-modal activity-based sorting.

Hamid Rasoulimehrabani, Alessandra Riva, Deniz Inan, Adnan Hodžić, Bela Hausmann, Georgi Nikolov, Sanaz Khadem, Norbert Hieger, Julia Wiesenbauer, Christina Kaiser and 3 more

Abstract read
In one paragraph

Article in Gut microbes, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Hamid RasoulimehrabaniCenter for Microbiology and Environmental Systems Science, Department of Microbiology and Ecosystem Science, University of Vienna, Vienna, Austria.
Alessandra RivaCenter for Microbiology and Environmental Systems Science, Department of Microbiology and Ecosystem Science, University of Vienna, Vienna, Austria.
Deniz InanCenter for Microbiology and Environmental Systems Science, Department of Microbiology and Ecosystem Science, University of Vienna, Vienna, Austria.
Adnan HodžićCenter for Microbiology and Environmental Systems Science, Department of Microbiology and Ecosystem Science, University of Vienna, Vienna, Austria.
Bela HausmannJoint Microbiome Facility of the Medical University of Vienna and The University of Vienna, Vienna, Austria.
Georgi NikolovCenter for Microbiology and Environmental Systems Science, Department of Microbiology and Ecosystem Science, University of Vienna, Vienna, Austria.
Sanaz KhademCenter for Microbiology and Environmental Systems Science, Department of Microbiology and Ecosystem Science, University of Vienna, Vienna, Austria.
Norbert HiegerCenter for Microbiology and Environmental Systems Science, Department of Microbiology and Ecosystem Science, University of Vienna, Vienna, Austria.
Julia WiesenbauerCenter for Microbiology and Environmental Systems Science, Department of Microbiology and Ecosystem Science, University of Vienna, Vienna, Austria.
Christina KaiserCenter for Microbiology and Environmental Systems Science, Department of Microbiology and Ecosystem Science, University of Vienna, Vienna, Austria.
Verena FilzDepartment of Biological Chemistry, University of Vienna, Vienna, Austria.
Thomas BöttcherDepartment of Biological Chemistry, University of Vienna, Vienna, Austria.
David BerryCenter for Microbiology and Environmental Systems Science, Department of Microbiology and Ecosystem Science, University of Vienna, Vienna, Austria.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

There is much interest in the development of dietary supplements that selectively promote the growth of beneficial gut bacteria. The selectivity of many candidate prebiotics has, however, not been thoroughly investigated. Here, we evaluated stimulation of the human gut microbiota by the disaccharide lactulose using an

Indexed as

BacteriaGastrointestinal MicrobiomeLactuloseAdultFecesFemaleHumansMalePrebioticsLactulosePrebioticsBONCATkeystone speciesprebioticsRACSRaman microspectroscopy

Identifiers

PMID40576010
PMCPMC12218441

What Socratic holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.