Evidence mapPaperPMID 40577090Full record

SynthesisNutrition reviews2026

The Certainty of the Evidence on Plant- vs Meat-Predominant Dietary Patterns and Depression: An Umbrella Review.

Megan F Lee, Jessica Bayes, Ahmed A Moustafa, Maximilian A Storz, Talitha Best

Abstract readSystematic Review
In one paragraph

Synthesis in Nutrition reviews, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Megan F LeeFaculty of Society and Design, Bond University, Gold Coast, QLD 4226, Australia.ORCID 0000-0001-7531-5312
Jessica BayesSouthern Cross University, School of Health, Lismore, NSW 2480, Australia.ORCID 0000-0003-0601-6129
Ahmed A MoustafaFaculty of Society and Design, Bond University, Gold Coast, QLD 4226, Australia.ORCID 0000-0001-7841-7808
Maximilian A StorzCenter for Complementary Medicine, Department of Medicine II, Faculty of Medicine, Medical Center-University of Freiburg, University of Freiburg, Breisgau 79098, Germany.ORCID 0000-0003-3277-0301
Talitha BestNeuroHealth Lab, Appleton Institute, Central Queensland University, Brisbane, QLD 4000, Australia.ORCID 0000-0001-8849-1411

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

contextDiets rich in plant foods are associated with reduced risk of depressive symptoms. However, previous studies have reported greater depressive symptomology in patients who follow a plant-predominant dietary pattern. Meta-analyses and systematic reviews of associations of plant- and meat-predominant diets and depression have highlighted conflicting results.

objectivesIn this umbrella review we applied A Measurement Tool to Assess Systematic Reviews 2 (AMSTAR2) to explore the state of evidence regarding possible associations of plant- and meat-predominant dietary patterns with depression. DATA SOURCES: Six databases were searched from the date of inception to January 2025: CINAHL, MEDLINE, PsycINFO, Psychology and Behavioral Sciences Collection, Scopus, and Web of Science. DATA EXTRACTION: Data were extracted by 2 independent researchers using Covidence software. DATA ANALYSIS: The search revealed 104 studies, of which 9 met inclusion criteria. Data were synthesized and narratively grouped by plant-predominant and meat-predominant dietary patterns.

conclusionsFive articles reported associations between plant- and meat-predominant dietary patterns and depression, 4 reported that plant-predominant dietary patterns increased depression, and 5 found conflicting or no associations. Similar systematic search terms, overlap of primary studies, and short timeframes between reviews raise concerns about the validity and scientific contribution of repeated systematic review of this topic. To address these concerns, we highlight the need for greater awareness of methodological issues, including high reliance on observational studies, high levels of heterogeneity, imprecision of measurement tools, and lack of measurement of dietary adherence and composition.

Indexed as

DepressionDietDiet, VegetarianMeatFeeding BehaviorHumansdepressive symptomsomnivoreplant-basedveganvegetarian

Identifiers

PMID40577090
PMCPMC13016671

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.