Evidence mapPaperPMID 40577339Full record

ArticlePLOS digital health2025

Determinants of photoplethysmography signal quality at the wrist.

Peter H Charlton, Vaidotas Marozas, Elisa Mejía-Mejía, Panicos A Kyriacou, Jonathan Mant

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Article in PLOS digital health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Peter H CharltonDepartment of Public Health and Primary Care, University of Cambridge, Cambridge, United Kingdom.ORCID https://orcid.org/0000-0003-3836-8655
Vaidotas MarozasBiomedical Engineering Institute, Kaunas University of Technology, Kaunas, Lithuania.
Elisa Mejía-MejíaRush Alzheimer's Disease Center, Rush University Medical Center, Chicago, Illinois, United States of America.
Panicos A KyriacouResearch Centre for Biomedical Engineering, City, University of London, London, United Kingdom.
Jonathan MantDepartment of Public Health and Primary Care, University of Cambridge, Cambridge, United Kingdom.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Wrist photoplethysmogram (PPG) signals are widely used for physiological monitoring in consumer devices. However, the PPG is highly susceptible to noise, which can reduce the accuracy of monitored parameters. The aim of this study was to identify factors which influence PPG signal quality. Data from the Aurora-BP dataset were used, consisting of reflectance wrist PPG signals measured from 1,142 subjects of varying ages and health statuses. Measurements were acquired in supine, sitting, and standing postures, and with the sensor held at different heights. Three signal quality metrics were calculated: the signal-to-noise ratio (SNR), the perfusion index (PI), and the template-matching correlation coefficient (TMCC). When comparing between postures with the sensor held at a natural height, quality was greatest in the supine position (SNR: 18.6 dB), followed by sitting with the arm resting in the lap (13.7 dB), and lowest whilst standing with the arm hanging alongside (9.0 dB) (p < 0.001). Signal quality increased as the arm was raised to heart height: whilst sitting, quality was lowest with the arm alongside the body (10.5 dB), and increased when the sensor was held in the lap (13.7 dB) and at heart height (15.5 dB) (p < 0.001). Similar trends were observed for the TMCC and PI. Findings were mixed for the influence of participant characteristics on signal quality. The SNR and TMCC, but not the PI, increased with age. The SNR either decreased or remained constant at darker skin tones when controlling for PPG DC amplitude, compared to constant or increased when allowing DC amplitude to vary. In conclusion, this study identified the impacts of posture and sensor height on signal quality, with highest qualities observed in the supine posture and with the sensor at heart height. It also highlights the importance of adjusting LED light intensity to maintain signal quality across skin tones.

Identifiers

PMID40577339
PMCPMC12204546

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.