Evidence map›Paper›PMID 40577472›Full record

ArticleScience advances2025

Hepatic NMNAT1 is required to defend against alcohol-associated fatty liver disease.

Qinchao Ding, Feiwei Cao, Hui Zhuge, Shanglei Lai, Wenjing Cao, Haibin Wei, Rui Guo, Jiannan Qiu, Qing Song, Liuhua Pei and 6 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Science advances, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Antioxidants (Basel, Switzerland) · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Qinchao DingSchool of Public Health, Zhejiang Chinese Medical University, Hangzhou, Zhejiang, PR. China.ORCID 0000-0001-8664-5368
Feiwei CaoSchool of Public Health, Zhejiang Chinese Medical University, Hangzhou, Zhejiang, PR. China.ORCID 0000-0002-2093-2767
Hui ZhugeSchool of Life Science, Zhejiang Chinese Medical University, Hangzhou, Zhejiang, PR. China.ORCID 0009-0003-5011-0929
Shanglei LaiSchool of Life Science, Zhejiang Chinese Medical University, Hangzhou, Zhejiang, PR. China.
Wenjing CaoSchool of Public Health, Zhejiang Chinese Medical University, Hangzhou, Zhejiang, PR. China.
Haibin WeiSchool of Life Science, Zhejiang Chinese Medical University, Hangzhou, Zhejiang, PR. China.ORCID 0000-0003-0519-4265
Rui GuoSchool of Public Health, Zhejiang Chinese Medical University, Hangzhou, Zhejiang, PR. China.
Jiannan QiuSchool of Life Science, Zhejiang Chinese Medical University, Hangzhou, Zhejiang, PR. China.
Qing SongSchool of Public Health, Zhejiang Chinese Medical University, Hangzhou, Zhejiang, PR. China.ORCID 0000-0002-9262-9513
Liuhua PeiSchool of Public Health, Zhejiang Chinese Medical University, Hangzhou, Zhejiang, PR. China.ORCID 0009-0003-6524-2502
Chaolan LiSchool of Public Health, Zhejiang Chinese Medical University, Hangzhou, Zhejiang, PR. China.ORCID 0000-0001-5607-4015
Caijuan SiDepartment of Clinical Nutrition, Affiliated Zhejiang Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, PR. China.
Zhaoli SunDepartment of Surgery, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Zhenyuan SongDepartment of Kinesiology and Nutrition, University of Illinois at Chicago, Chicago, IL, USA.ORCID 0000-0001-8750-5762
Xiaobing DouSchool of Life Science, Zhejiang Chinese Medical University, Hangzhou, Zhejiang, PR. China.ORCID 0000-0002-2465-3079
Songtao LiSchool of Public Health, Zhejiang Chinese Medical University, Hangzhou, Zhejiang, PR. China.ORCID 0000-0002-2926-673X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nicotinamide mononucleotide adenylyltransferase 1 (NMNAT1), a nicotinamide adenine dinucleotide (NAD

Indexed as

Fatty Liver, AlcoholicLiverNicotinamide-Nucleotide AdenylyltransferaseAnimalsDisease Models, AnimalHepatocytesHumansInterferon Regulatory Factor-1Lipid MetabolismMaleMiceMice, Inbred C57BLMice, KnockoutInterferon Regulatory Factor-1Nicotinamide-Nucleotide Adenylyltransferase

Identifiers

PMID40577472
PMCPMC12204165

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.