Evidence map›Paper›PMID 40579029›Full record

Observational studyIn vivo (Athens, Greece)

The Association of Glucose Metabolism Disorders and Acne in Women With Polycystic Ovary Syndrome (PCOS).

Eftichia Damoulaki, Dimos Sioutis, Eleni P Georgiadi, Eftichios Trakakis, Georgios Mastorakos, Alexander Katoulis, Konstantinos Louis, Dimitrios Panagiotopoulos, Nikolaos Machairiotis, Vasilios Pergaliotis and 2 more

Abstract readObservational Study
PubMed Full text at PMC Publisher
In one paragraph

Observational study in In vivo (Athens, Greece). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Eftichia DamoulakiThird Department of Obstetrics and Gynecology, University General Hospital "ATTIKON", Medical School, National and Kapodistrian University of Athens, Athens, Greece.
Dimos Sioutis *Third Department of Obstetrics and Gynecology, University General Hospital "ATTIKON", Medical School, National and Kapodistrian University of Athens, Athens, Greece.
Eleni P Georgiadi *Third Department of Obstetrics and Gynecology, University General Hospital "ATTIKON", Medical School, National and Kapodistrian University of Athens, Athens, Greece; elgeorg.med@gmail.com.
Eftichios TrakakisThird Department of Obstetrics and Gynecology, University General Hospital "ATTIKON", Medical School, National and Kapodistrian University of Athens, Athens, Greece.
Georgios MastorakosUnit of Endocrinology, Diabetes Mellitus, and Metabolism, Aretaieion Hospital, National and Kapodistrian University of Athens, Athens, Greece.
Alexander KatoulisSecond Department of Dermatology and Venereology, Attikon University General Hospital, School of Medicine, National and Kapodistrian University of Athens, Athens, Greece.
Konstantinos LouisThird Department of Obstetrics and Gynecology, University General Hospital "ATTIKON", Medical School, National and Kapodistrian University of Athens, Athens, Greece.
Dimitrios PanagiotopoulosThird Department of Obstetrics and Gynecology, University General Hospital "ATTIKON", Medical School, National and Kapodistrian University of Athens, Athens, Greece.
Nikolaos MachairiotisThird Department of Obstetrics and Gynecology, University General Hospital "ATTIKON", Medical School, National and Kapodistrian University of Athens, Athens, Greece.
Vasilios PergaliotisFirst Department of Obstetrics and Gynecology, Division of Gynecologic Oncology, "Alexandra" General Hospital, National and Kapodistrian University of Athens, Athens, Greece.
Periklis PanagopoulosThird Department of Obstetrics and Gynecology, University General Hospital "ATTIKON", Medical School, National and Kapodistrian University of Athens, Athens, Greece.
Chrysi ChristodoulakiThird Department of Obstetrics and Gynecology, University General Hospital "ATTIKON", Medical School, National and Kapodistrian University of Athens, Athens, Greece.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

aimAcne is a common dermatological manifestation of polycystic ovary syndrome (PCOS), a prevalent endocrinological disorder among women of reproductive age. A growing body of evidence highlights glucose metabolism disorders, including insulin resistance, in the context of PCOS. This study aimed to investigate the association of acne and its severity with insulin resistance in a population of women with PCOS. PATIENTS AND

methodsA total of 305 women with PCOS aged between 17-35 years were included in this retrospective observational study. Anthropometric, hormonal, biochemical, and ultrasonographic markers of PCOS were analyzed in relation to insulin resistance indices, including HOMA-IR and QUICKI.

resultsAcne was present in 56.4% of participants, with 52.1% exhibiting mild and 4.3% severe cases. Younger age (

conclusionThis study indicates the association between insulin resistance and hyperandrogonemia with both the presence and severity of acne in PCOS. These findings align with contemporary literature and underscore the importance of addressing the hormonal and metabolic factors in the etiological management of acne in PCOS.

Indexed as

Acne VulgarisGlucose Metabolism DisordersPolycystic Ovary SyndromeAdolescentAdultBiomarkersBlood GlucoseDehydroepiandrosterone SulfateFemaleHumansInsulin ResistanceRetrospective StudiesSeverity of Illness IndexYoung AdultBiomarkersBlood GlucoseDehydroepiandrosterone Sulfateacnehyperandrogenisminsulin resistancemetabolismmetforminPCOS

Identifiers

PMID40579029
PMCPMC12223598

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.