Evidence map›Paper›PMID 40580237›Full record

ArticleAging clinical and experimental research2025

Sarcopenia association with physical and psychological indices in community-dwelling aged population, Birjand Longitudinal Aging Study (BLAS).

Amir Nasrollahizadeh, Sepide Javankiani, Pouya Ebrahimi, Farshad Sharifi, Parnian Soltani, Majid Amiri, Mitra Moodi, Masoumeh Khorashadizadeh, Hossein Fakhrzadeh, Pedram Ramezani and 4 more

Abstract read
In one paragraph

Article in Aging clinical and experimental research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Amir Nasrollahizadeh *Non-Communicable Diseases Research Center, Endocrinology and Metabolism Population Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran.
Sepide Javankiani *Non-Communicable Diseases Research Center, Endocrinology and Metabolism Population Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran.
Pouya EbrahimiNon-Communicable Diseases Research Center, Endocrinology and Metabolism Population Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran.
Farshad SharifiElderly Health Research Center, Endocrinology and Metabolism Population Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran.
Parnian SoltaniCardiovascular Diseases Research Institute, Tehran Heart Center, Tehran University of Medical Sciences, Tehran, Iran.
Majid AmiriDepartment of Psychology, Payame Noor University, Tehran, Iran.
Mitra MoodiBirjand Geriatric Health Research Center, Birjand University of Medical Sciences, Birjand, Iran.
Masoumeh KhorashadizadehBirjand Geriatric Health Research Center, Birjand University of Medical Sciences, Birjand, Iran.
Hossein FakhrzadehDepartment of Gerontology, School of Rehabilitation, Tehran University of Medical Sciences, Tehran, Iran.
Pedram RamezaniNon-Communicable Diseases Research Center, Endocrinology and Metabolism Population Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran.
Fatemeh NaderiDepartment of Cardiology, Rajaie Cardiovascular, Medical and Research Center, Tehran, Iran.
Maryam TaheriNon-Communicable Diseases Research Center, Endocrinology and Metabolism Population Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran.
Mahbube EbrahimpurEndocrinology and Metabolism Research center, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran. m-ebrahimpur@tums.ac.ir.
Moloud PayabNon-Communicable Diseases Research Center, Endocrinology and Metabolism Population Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran. mpayab@tums.ac.ir.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSarcopenia is a progressive syndrome associated with adverse outcomes in older adults. This study aimed to assess the prevalence of sarcopenia and its associated risk and protective factors among community-dwelling elderly individuals.

methodsAs a part of the Birjand Longitudinal Aging Study (BLAS), this retrospective cross-sectional study assesses patients older than 60 years old. Basic characteristics, nutritional status, comorbidities, and sociodemographic data were collected. Logistic regression analyses were performed to identify factors associated with sarcopenia severity.

resultsA total of 1,348 participants (mean age: 69.73 ± 7.53 years) were classified into four groups: robust (58.85%), probable sarcopenia (31.03%), sarcopenia (4.76%), and severe sarcopenia (5.36%). On univariate analysis, being overweight or obese, any formal education, regular physical activity, and hypertension were accompanied by lower odds of sarcopenia, whereas dementia and anemia increased its odds. In the fully adjusted model, age > 70 years (OR 1.39, 95% CI 1.05-1.83) and > 80 years (OR 4.93, 95% CI 3.15-7.71), malnutrition risk (OR 1.36, 95% CI 1.02-1.82), living alone (OR 1.88, 95% CI 1.12-3.22) and dementia (OR 1.03 per 6-CIT point, 95% CI 1.01-1.05) were independent risk factors, while education lower than diploma (OR 0.63, 95% CI 0.46-0.86) and diploma (OR 0.39, 95% CI 0.22-0.67), exercise more than once per week (with different ORs regarding variable physical activity frequencies) and hypertension (OR = 0.62, 95% CI: 0.47-0.81, P-value < 0.01) were related to lower odds of sarcopenia.

conclusionsThose aged > 70, at risk of malnutrition, and having dementia had higher odds of sarcopenia. In contrast, having an educational level of a diploma or lower, ≥ one session of physical activity per week, and having hypertension showed a reverse association with sarcopenia. Findings underscore the importance of targeted interventions to mitigate sarcopenia risk in aging populations.

Indexed as

AgingSarcopeniaAgedAged, 80 and overCross-Sectional StudiesExerciseFemaleHumansIndependent LivingLongitudinal StudiesMaleMiddle AgedNutritional StatusPrevalenceRetrospective StudiesRisk FactorsAgedChronic diseasesGeriatricsSarcopenia

Identifiers

PMID40580237
PMCPMC12206203

What Socratic holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.