Evidence mapPaperPMID 40580265Full record

ArticleAging clinical and experimental research2025

Association between Dynapenic abdominal obesity and fall risk among older adults: a longitudinal study in Birjand.

Hadiseh Rahimi Chaksari, Pouya Ebrahimi, Tahereh Yavari, Farshad Sharifi, Pedram Ramezai, Reza Pirdehghan, Fatemeh Naderi, Mitra Moodi, Masoumeh Khorashadizadeh, Moloud Payab and 1 more

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Article in Aging clinical and experimental research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

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4citing papers in PubMed
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1 · What the graph read from it

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3 · Its place in the literature

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4 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

11 authors.

Hadiseh Rahimi ChaksariEndocrinology and Metabolism Research Center, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences (TUMS), Tehran, Iran.
Pouya EbrahimiCardiovascular Disease Research Institute, Tehran Heart Center, Tehran University of Medical Sciences, Tehran, Iran.
Tahereh YavariDepartment of Internal Medicine, Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran.
Farshad SharifiElderly Health Research Center, Endocrinology and Metabolism Population Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran.
Pedram RamezaiElderly Health Research Center, Endocrinology and Metabolism Population Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran.
Reza PirdehghanFaculty of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Fatemeh NaderiPediatric Cardiovascular Research Center, Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran.
Mitra MoodiGeriatric Health Research Center, Birjand University of Medical Sciences, Birjand, Iran.
Masoumeh KhorashadizadehSocial Determinants of Health Research Center, Birjand University of Medical Sciences, Birjand, Iran.
Moloud PayabNon-Communicable Diseases Research Center, Endocrinology and Metabolism Population Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran. mpayab@tums.ac.ir.
Mahbube Ebrahim PourElderly Health Research Center, Endocrinology and Metabolism Population Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran. m-ebrahimpur@tums.ac.ir.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionDynapenic abdominal obesity (DAO) is the coexistence of obesity and dynapenia, defined as muscle weakness. Both abdominal obesity and dynapenia may contribute to falls in older adults. This study assesses the relationship between DAO and the risk of falls in the population ≥ over 60 who participated in the Birjand Longitudinal Aged Study (BLAS) trial.

methodsThis prospective cohort study involves 1,418 elderly participants aged ≥ 60. The sample, representative of the aged population BLAS program, was selected using stratified random cluster sampling. Data on fall events - including the date, time, cause, and associated injuries - were collected through a structured researcher-designed data collection form via telephone contact with the participants or their families. Clinical examination findings and paraclinical test results per the study protocol were also available to researchers.

resultsOf the 1,418 participants, 697 (51.71%) were women, and 651 (48.29%) were men, with a mean age of 69.73. The presence of DAO was significantly associated with a higher risk of falls, with a coefficient of OR = 2.65 (CI 95% 1.03-6.84, P = 0.044). Among the participants, 757(56.2%), 422 (31.3%), and 169 (12.5%) fell in the age groups between 60 and 69, 70-79, and ≥ 80 years, respectively. Male gender (OR: 0.45, 95%CI: 0.23-0.90, P-value: 0.23), on the other hand, was linked to a lower risk of falls, and this association was statistically significant. Furthermore, a higher risk of falls was observed among those with higher scores on the "Time to Get Up and Go" test (OR: 1.80, 95%CI: 1.11-2.92, P-value: 0.16), as well as those with depression (OR: 2.13, 95%CI: 1.30-3.49, P-value: 0.003), and anemia (OR: 1.89, 95%CI: 1.02-3.50, P-value: 0.043), with coefficients of 0.59, 0.75, and 0.63, respectively, all of which were statistically significant.

conclusionThis study's findings suggest that DAO is a significant risk factor for falls in elderly individuals. Moreover, the male gender appears to be protected against falls. In contrast, factors such as depression, higher risk based on the Time to "Get Up and go" test, and anemia are associated with elevated risk. These factors may be crucial in understanding the relationship between Dynapenic abdominal obesity and fall risk in the elderly. They can help stratify aged adults to prevent falls more efficiently. CLINICAL TRIAL NUMBER: Not applicable.

Indexed as

Accidental FallsMuscle WeaknessObesity, AbdominalAgedAged, 80 and overFemaleHumansLongitudinal StudiesMaleMiddle AgedProspective StudiesRisk Factors

Identifiers

PMID40580265
PMCPMC12206166

What Socratic holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.