Evidence map›Paper›PMID 40581821›Full record

ArticlePlant communications2025

CRISPR-Cas9-mediated knockup of OsDREB1C enhances rice yield without compromising grain quality.

Yanmin Luo, Xiaodeng Zhan, Yingxin Zhang, Beifang Wang, Guanqi Wang, Yue Zhang, Guzi Li, Qunen Liu, Xihong Shen, Daibo Chen and 6 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Plant communications, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Yanmin LuoState Key Laboratory of Rice Biology and Breeding, China National Rice Research Institute, Hangzhou 311400, China; Northern Rice Research Center of Baoqing, Shuangyashan 155600, China; Key Laboratory of Northern Japonica Rice Research in Heilongjiang Province, Baoqing Northern Rice Research Center, Baoqing, Heilongjiang 155600, China.
Xiaodeng ZhanState Key Laboratory of Rice Biology and Breeding, China National Rice Research Institute, Hangzhou 311400, China.
Yingxin ZhangState Key Laboratory of Rice Biology and Breeding, China National Rice Research Institute, Hangzhou 311400, China.
Beifang WangState Key Laboratory of Rice Biology and Breeding, China National Rice Research Institute, Hangzhou 311400, China.
Guanqi WangState Key Laboratory of Rice Biology and Breeding, China National Rice Research Institute, Hangzhou 311400, China.
Yue ZhangState Key Laboratory of Rice Biology and Breeding, China National Rice Research Institute, Hangzhou 311400, China.
Guzi LiState Key Laboratory of Rice Biology and Breeding, China National Rice Research Institute, Hangzhou 311400, China.
Qunen LiuState Key Laboratory of Rice Biology and Breeding, China National Rice Research Institute, Hangzhou 311400, China.
Xihong ShenState Key Laboratory of Rice Biology and Breeding, China National Rice Research Institute, Hangzhou 311400, China.
Daibo ChenState Key Laboratory of Rice Biology and Breeding, China National Rice Research Institute, Hangzhou 311400, China.
Yongbo HongState Key Laboratory of Rice Biology and Breeding, China National Rice Research Institute, Hangzhou 311400, China; National Nanfan Research Institute (Sanya), Chinese Academy of Agricultural Sciences, Sanya 572025, China.
Weixun WuState Key Laboratory of Rice Biology and Breeding, China National Rice Research Institute, Hangzhou 311400, China.
Guoyou YeInternational Rice Research Institute, Los Banos, Laguna 4031, Philippines.
Shihua ChengState Key Laboratory of Rice Biology and Breeding, China National Rice Research Institute, Hangzhou 311400, China.
Gang PanDepartment of Agronomy, Zhejiang University, Hangzhou 310058, China. Electronic address: pangang12@zju.edu.cn.
Liyong CaoState Key Laboratory of Rice Biology and Breeding, China National Rice Research Institute, Hangzhou 311400, China; Northern Rice Research Center of Baoqing, Shuangyashan 155600, China; National Nanfan Research Institute (Sanya), Chinese Academy of Agricultural Sciences, Sanya 572025, China; Key Laboratory of Northern Japonica Rice Research in Heilongjiang Province, Baoqing Northern Rice Research Center, Baoqing, Heilongjiang 155600, China. Electronic address: caoliyong@caas.cn.

Funding

Non-US Government Research Support type
6 · The paper itself

Abstract

This study presents a CRISPR-Cas9-based strategy for engineering structural variations in the OsDREB1C gene in rice, leading to a yield increase of over 20% without compromising grain quality. The resulting homozygous plants are transgene-free, highlighting the potential of this approach for precise and effective crop improvement.

Indexed as

CRISPR-Cas SystemsEdible GrainOryzaPlant ProteinsGene EditingGene Knock-In TechniquesPlants, Genetically ModifiedPlant Proteins

Identifiers

PMID40581821
PMCPMC12545883

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.