Evidence mapPaperPMID 40583191Full record

ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2025

POLE Deficiency Exacerbates Diesel Engine Exhaust-Induced Genomic Instability and Malignant Transformation of Bronchial Epithelial Cells.

Pimei Zhang, Zhaoxu Wu, Qiang Ju, Nuo Xu, Xian Chen, Hongguang Chen, Shuaishuai Yang, Jing Ji, Yanjie Zhao

Abstract read
In one paragraph

Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Pimei ZhangDepartment of Blood Transfusion, The Affiliated Hospital of Qingdao University, Qingdao University, Qingdao, Shandong, 266000, China.
Zhaoxu WuDepartment of Blood Transfusion, The Affiliated Hospital of Qingdao University, Qingdao University, Qingdao, Shandong, 266000, China.
Qiang JuDepartment of Blood Transfusion, The Affiliated Hospital of Qingdao University, Qingdao University, Qingdao, Shandong, 266000, China.
Nuo XuSchool of Public Health, Qingdao University, Qingdao, Shandong, 266021, China.
Xian ChenSchool of Public Health, Qingdao University, Qingdao, Shandong, 266021, China.
Hongguang ChenSchool of Public Health, Qingdao University, Qingdao, Shandong, 266021, China.
Shuaishuai YangSchool of Public Health, Qingdao University, Qingdao, Shandong, 266021, China.
Jing JiSchool of Public Health, Qingdao University, Qingdao, Shandong, 266021, China.
Yanjie ZhaoSchool of Public Health, Qingdao University, Qingdao, Shandong, 266021, China.ORCID https://orcid.org/0000-0002-6618-2447

Funding

National Natural Science Foundation for Young Scientists of China 82203761National Natural Science Foundation of China 82173495Natural Science Foundation of Shandong Province ZR2024MH133
6 · The paper itself

Abstract

Diesel engine exhaust (DEE) is classified as a Group I carcinogen, yet direct experimental evidence that DEE induce carcinogenesis is lacking. Here, it is innovatively discovered that 120 µg mL

Indexed as

BronchiCell Transformation, NeoplasticEpithelial CellsGenomic InstabilityLung NeoplasmsVehicle EmissionsAnimalsDNA DamageHumansMiceVehicle EmissionsDEE‐OEsgenomic instabilitymalignant transformationPOLE

Identifiers

PMID40583191
PMCPMC12463065

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.