ArticleFood chemistry: X2025
Liposome encapsulation for casein-derived peptides: Release behavior,
Article in Food chemistry: X, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
8 citing papers in PubMed.
- Liposomal Delivery Enhances the Effects of a Collagen Tripeptide-Containing Formulation on Dermal Structure and Optical Skin Parameters: A Randomized, Double-Blind, Placebo-Controlled Trial.Journal of cosmetic dermatology · 2026Trial
- Protein hydrolysates derived from poultry by-products as nutraceuticals: Bioactive potential, limitations, safety considerations, and commercialization perspectives.Poultry science · 2026Review
- Oral Delivery Systems for Food-Derived Bioactive Peptides: Enhancing Stability, Bioavailability, and Health Benefits.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Review
- Polymer-Based and Biomaterial Encapsulation of Probiotics for Improved Viability.Probiotics and antimicrobial proteins · 2026Review
- Enzyme-Loaded Liposomal Edible Hydrogel Films to Enhance Lactase Activity in Perline Mozzarella.Gels (Basel, Switzerland) · 2026Article
- From Ancient Fruit to Functional Innovation: Liposomal Delivery of Haritaki (Antioxidants (Basel, Switzerland) · 2026Article
- Recent Advances in Exploring Casein Peptide Regulation of Inflammatory Bowel Disease from an Intestinal Barrier Perspective: Correlations, Mechanisms, Challenges and Solutions.Foods (Basel, Switzerland) · 2026Review
- Stimuli-Responsive Cell-Mimetic Vesicles for Advanced Pharmaceutical Systems.International journal of nanomedicine · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Protein-derived bioactive peptides hold great potential for promoting health while face significant challenges during digestion, including structural degradation by gastrointestinal enzymes and limited stability, which hinder their effective utilization. Encapsulation technology offers a promising solution to protect bioactive peptides and ensure their targeted delivery. In this study, casein peptides (CP) were encapsulated into liposomes (CPL) prepared using the thin-film hydration method. The preparation conditions were optimized through response surface methodology, with the following parameters identified: a lecithin-to-cholesterol mass ratio of 3.0, a peptide solution concentration of 0.65 mg/mL, and a wall-to-core material volume ratio of 4.0. Validation experiments confirmed the optimized CPL formulation, resulting in liposomes with an average particle size of 86.13 ± 0.62 nm and an encapsulation efficiency at 87.29 ± 0.82 %. Comprehensive characterization of CPL was conducted using transmission electron microscopy (TEM), differential scanning calorimetry (DSC), and fourier transform infrared spectroscopy (FTIR) techniques. The results demonstrated that CPL provided strong protection for CP against degradation by gastrointestinal enzymes, allowing controlled release in the intestine. This targeted release facilitated interactions with gut microbiota, leading to improved nutrient absorption and modulation of gut health. These findings highlight the potential of liposomal encapsulation to enhance the bioavailability and functional properties of bioactive peptides, paving the way for their broader application in health-related formulations.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.