ReviewFrontiers in nutrition2025
Impacts of amino acid supplementation on renal function and nutritional parameters in patients with renal insufficiency: bibliometric analysis and meta-analysis.
Review in Frontiers in nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Evaluating a Clinical Decision Support System for Optimizing Total Parenteral Nutrition in Adult Oncology Patients.Nutrients · 2026Article
- Integrated transcriptomic and single-cell RNA-seq analysis identifies CLCNKB, KLK1 and PLEKHA4 as key gene of AKI-to-CKD progression.Frontiers in immunology · 2025Article
Corrections and comments
- Erratum issued
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objective: The aim of this study was to summarize the effects of amino acids (AA) on renal function and nutritional indices in patients with renal insufficiency (RI) after treatment and to analyze the development trend in this field. Methods: The bibliometric evaluation of scholarly contributions in this field was conducted using the Web of Science database, with data analyzed via Bibliometrix and VOSviewer software. The randomized controlled trials (RCTs) published before January 13, 2025, were systematically retrieved from Embase, PubMed, and the Cochrane Library and meta-analyses were performed using Review Manager 5.4 software. Results: Key areas of focus included oxidative stress, chronic renal failure, hemodialysis, inflammation, chronic kidney disease, risk, plasma, progression, L-arginine, disease, and renal failure. Nine RCTs involving 407 participants were included, AA administration demonstrated significant effects compared to placebo: Increased blood urea nitrogen (MD: 4.21, 95% CI: 1.08 to 7.35, Conclusion: These findings suggest that AA supplementation may partially improve renal function in RI patients. The progression and possible mechanisms of chronic kidney disease, as well as the search for new biomarkers, will be the trend of research and development in this field.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.