Evidence map›Paper›PMID 40584263›Full record

ArticleJHEP reports : innovation in hepatology2025

Safety, efficacy, and outcomes of invasive coronary angiography in liver transplant candidates.

Carme Ginard, Giulia Pagano, Salvatore Brugaletta, Annabel Blasi, Marta Sánchez-Ric, Ander Regueiro, Roger Pujol, Sergio Rodriguez-Tajes, Pablo Ruiz, Jordi Colmenero and 1 more

Abstract read
In one paragraph

Article in JHEP reports : innovation in hepatology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Carme GinardDepartment of Medicine, Faculty of Medicine and Health Sciences, University of Barcelona, Catalonia, Spain.
Giulia PaganoLiver Unit, Hospital Clínic, Barcelona, Spain.
Salvatore BrugalettaDepartment of Cardiology, Hospital Clínic, Barcelona, Spain.
Annabel BlasiDepartment of Anesthesiology, Hospital Clínic, Barcelona, Spain.
Marta Sánchez-RicLiver Unit, Hospital Clínic, Barcelona, Spain.
Ander RegueiroDepartment of Cardiology, Hospital Clínic, Barcelona, Spain.
Roger PujolDepartment of Anesthesiology, Hospital Clínic, Barcelona, Spain.
Sergio Rodriguez-TajesLiver Unit, Hospital Clínic, Barcelona, Spain.
Pablo RuizLiver Unit, Hospital Clínic, Barcelona, Spain.
Jordi ColmeneroDepartment of Medicine, Faculty of Medicine and Health Sciences, University of Barcelona, Catalonia, Spain.
Gonzalo CrespoDepartment of Medicine, Faculty of Medicine and Health Sciences, University of Barcelona, Catalonia, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background & Aims: Invasive coronary angiography (ICA) with/without percutaneous coronary intervention (PCI) is recommended in liver transplant (LT) candidates at risk of silent coronary artery disease (CAD). The outcomes and safety of this approach have been scarcely analyzed in Europe. Methods: This retrospective, single-center study included all patients assessed as LT candidates between July 2015 and December 2022. Outcomes before and after LT were compared between patients with and without ICA as part of pre-LT assessment. Findings and outcomes of ICA were recorded. Results: A total of 912 patients were considered for LT, of whom 202 had an ICA. Patients with ICA more frequently presented contraindications for LT ( Conclusions: In a contemporary cohort of LT candidates, ICA was associated with a low incidence of complications, although some of these, related to DAPT, can be life-threatening. The burden of disease in ICA correlates with the incidence of post-LT CVEs, although this did not result in a higher mortality. Impact and implications: Invasive coronary angiography (ICA) is performed in potential liver transplant (LT) candidates to identify severe coronary artery disease that may either be treated to permit LT or contraindicate LT if untreatable, but its safety and outcomes are not well defined. We show that ICA is associated with a low incidence of complications in LT candidates, although severe coronary artery disease requiring percutaneous treatment followed by dual antiplatelet therapy increased the risk of severe complications. In addition, ICA identifies patients with untreatable disease that can contraindicate LT. Finally, the higher the burden of disease on ICA, the higher the incidence of post-LT cardiovascular events, although this was not associated with increased post-LT mortality. These results support the use of ICA in LT candidates, although being aware of the potential risks is crucial for physicians and patients.

Indexed as

CardiovascularCoronary angiographyDrug-eluting stentLiver transplantation

Identifiers

PMID40584263
PMCPMC12205637

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.