Evidence map›Paper›PMID 40584969›Full record

ArticleJournal of Alzheimer's disease reports

Purpose and meaning in life and the trajectory of episodic memory in eight longitudinal samples.

Angelina R Sutin, Justin Brown, Martina Luchetti, Yannick Stephan, Antonio Terracciano

Abstract read
In one paragraph

Article in Journal of Alzheimer's disease reports. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Angelina R SutinDepartment of Behavioral Sciences and Social Medicine, Florida State University College of Medicine, Tallahassee, FL, USA.ORCID https://orcid.org/0000-0002-1824-8974
Justin BrownDepartment of Behavioral Sciences and Social Medicine, Florida State University College of Medicine, Tallahassee, FL, USA.
Martina LuchettiDepartment of Behavioral Sciences and Social Medicine, Florida State University College of Medicine, Tallahassee, FL, USA.ORCID https://orcid.org/0000-0002-7370-8443
Yannick StephanEuromov, University of Montpellier, Montpellier, France.
Antonio TerraccianoDepartment of Geriatrics, Florida State University College of Medicine, Tallahassee, FL, USA.ORCID https://orcid.org/0000-0001-5799-8885

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Higher purpose and meaning in life are associated with lower risk of Alzheimer's disease and related dementias. Change in memory over time may be an early indicator of oncoming cognitive impairment and, even in the absence of impairment, memory change is associated with reduced quality of life in older adulthood. Purpose has been associated with better episodic memory performance when measured concurrently; less is known about whether purpose is associated with change in memory over time. Objective: To examine the association between purpose and declines in memory over time in multiple cohorts. Methods: The analyses included eight established cohort studies (total Results: A random-effects meta-analysis indicated that purpose was related to the level (intercept meta-analytic estimate = 0.26, Conclusions: Purpose in life is associated consistently with the average level of episodic memory but not how it changes over time. The association between purpose in life and lower risk of Alzheimer's disease may be due, in part, to the higher average level of episodic memory rather than less systematic decline in memory over time.

Indexed as

Alzheimer's diseaseepisodic memorylongitudinalmeaning in lifememory trajectorypurpose in life

Identifiers

PMID40584969
PMCPMC12202909

What Socratic holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.