Evidence map›Paper›PMID 40585387›Full record

ArticleBioactive materials2025

Multifunctional DNA hydrogels with light-triggered gas-therapy and controlled G-Exos release for infected wound healing.

Yuyun Ye, Yan Liu, Shengchao Ma, Xipeng Li, Wei Wang, Xu Chen, Judun Zheng, Zhijin Fan, Yideng Jiang, Yuhui Liao

Abstract read
In one paragraph

Article in Bioactive materials, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed.

  1. Review
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  3. Advances in Research onInternational journal of molecular sciences · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Yuyun YeInstitute for Engineering Medicine, Kunming Medical University, Kunming, 650500, China.
Yan LiuInstitute for Health Innovation & Technology, National University of Singapore, 117599, Singapore.
Shengchao MaNHC Key Laboratory of Metabolic Cardiovascular Diseases Research, Ningxia Key Laboratory of Vascular Injury and Repair Research, Ningxia Medical University, Yinchuan, 750004, China.
Xipeng LiInstitute for Engineering Medicine, Kunming Medical University, Kunming, 650500, China.
Wei WangInstitute for Engineering Medicine, Kunming Medical University, Kunming, 650500, China.
Xu ChenInstitute for Engineering Medicine, Kunming Medical University, Kunming, 650500, China.
Judun ZhengMolecular Diagnosis and Treatment Center for Infectious Diseases, Dermatology Hospital, Southern Medical University, Guangzhou, 510091, China.
Zhijin FanInstitute for Engineering Medicine, Kunming Medical University, Kunming, 650500, China.
Yideng JiangNHC Key Laboratory of Metabolic Cardiovascular Diseases Research, Ningxia Key Laboratory of Vascular Injury and Repair Research, Ningxia Medical University, Yinchuan, 750004, China.
Yuhui LiaoInstitute for Engineering Medicine, Kunming Medical University, Kunming, 650500, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Infectious wound healing remains a significant medical challenge due to chronic inflammation and bacterial colonization. Effective antimicrobial and anti-inflammatory therapies are essential to facilitate wound recovery. Herein, we introduce a highly biocompatible, ROS-responsive DNA hydrogel (LGAH), modified with aggregation-induced emission luminogens (AIEgen) and incorporating ginseng-derived exosomes (G-Exos) and nitric oxide (NO) donor-L-arginine (L-Arg) to promote healing of infected wounds. The hydrogel degrades in response to elevated ROS levels, releasing therapeutic agents. Upon laser irradiation, AIEgen generates

Indexed as

Aggregating-induced emission luminogenDNA hydrogelGas therapyGinseng-derived exosomesInfected wound healingTissue regeneration

Identifiers

PMID40585387
PMCPMC12206045

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.