Evidence map›Paper›PMID 40585774›Full record

ReviewExploration (Beijing, China)2025

Design Principles Of Inorganic-Protein Hybrid Materials for Biomedicine.

Hao Liu, Xiaohui Liu, Hui Jiang, Xuemei Wang

Abstract readReview
In one paragraph

Review in Exploration (Beijing, China), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Mechanobiological Dynamics-Inspired Mechanomodulatory Biomaterials.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Review
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Hao LiuState Key Laboratory of Bioelectronics (Chien-Shiung Wu Lab) School of Biological Science and Medical Engineering Southeast University Nanjing Jiangsu China.ORCID https://orcid.org/0000-0003-0266-6431
Xiaohui LiuState Key Laboratory of Bioelectronics (Chien-Shiung Wu Lab) School of Biological Science and Medical Engineering Southeast University Nanjing Jiangsu China.
Hui JiangState Key Laboratory of Bioelectronics (Chien-Shiung Wu Lab) School of Biological Science and Medical Engineering Southeast University Nanjing Jiangsu China.
Xuemei WangState Key Laboratory of Bioelectronics (Chien-Shiung Wu Lab) School of Biological Science and Medical Engineering Southeast University Nanjing Jiangsu China.ORCID https://orcid.org/0000-0001-6882-7774

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Inorganic protein hybrid materials (IPHMs) due to editable structure present unrivalled potential at the intersection of synthetic biology and materials science. The synthesis of IPHMs with a high degree of biosafety from bioactive units represents a shift in material design and synthesis. This paper focuses on a review of the structural basis and design principles of proteins for the synthesis of IPHMs with specific physical and chemical functions. It also provides a valuable reference for the design of emerging IPHMs through the conformational relationship of the IPHMs, which extends the potential applications of IPHMs. In addition, the construction strategy of the reaction system for the synthesis of hybrid materials is analyzed from the perspective of synthetic biology. The possibility of engineering and batch synthesis of IPHMs is discussed. Based on the physicochemical properties of different hybrid materials and the applied-oriented research on biomedical optical imaging and multimodal therapy, the idea of synthesis of in situ hybrid materials is proposed. Ultimately, the trends and challenges of synthetic biology for IPHMs are speculated in detail.

Indexed as

biosynthesisinterventional therapyliving materialsprotein coronassmart materials

Identifiers

PMID40585774
PMCPMC12199438

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.