Evidence map›Paper›PMID 40586015›Full record

ArticleCJC open2025

Center-Level Variation in the Development of Acute Kidney Injury Following Cardiac Operation.

Troy N Coaston, Joanna Curry, Amulya Vadlakonda, Saad Mallick, Giselle Porter, Corynn Branche, Nguyen Le, Peyman Benharash

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in CJC open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Troy N CoastonCardiovascular Outcomes Research Laboratories (CORELAB), David Geffen School of Medicine at University of California, Los Angeles, Los Angeles, California, USA.
Joanna CurryCardiovascular Outcomes Research Laboratories (CORELAB), David Geffen School of Medicine at University of California, Los Angeles, Los Angeles, California, USA.
Amulya VadlakondaCardiovascular Outcomes Research Laboratories (CORELAB), David Geffen School of Medicine at University of California, Los Angeles, Los Angeles, California, USA.
Saad MallickCardiovascular Outcomes Research Laboratories (CORELAB), David Geffen School of Medicine at University of California, Los Angeles, Los Angeles, California, USA.
Giselle PorterCardiovascular Outcomes Research Laboratories (CORELAB), David Geffen School of Medicine at University of California, Los Angeles, Los Angeles, California, USA.
Corynn BrancheCardiovascular Outcomes Research Laboratories (CORELAB), David Geffen School of Medicine at University of California, Los Angeles, Los Angeles, California, USA.
Nguyen LeCardiovascular Outcomes Research Laboratories (CORELAB), David Geffen School of Medicine at University of California, Los Angeles, Los Angeles, California, USA.
Peyman BenharashCardiovascular Outcomes Research Laboratories (CORELAB), David Geffen School of Medicine at University of California, Los Angeles, Los Angeles, California, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Acute kidney injury (AKI) is a frequent complication following cardiac surgery. However, factors associated with AKI remain poorly understood. In this national study, we evaluated centre-level variation in the incidence of AKI after elective cardiac surgery. Methods: Adult patients undergoing elective coronary artery bypass graft or valve operations with normal baseline renal function were identified in the 2010-2020 National Inpatient Sample. Multilevel mixed-effects models were utilized to rank hospitals based on estimated rate of AKI. The intraclass coefficient was used to estimate the level of variation attributable to hospital factors. High AKI centres (HACs) were defined as those within the highest decile of estimated AKI rate. The association between HAC status, in-hospital mortality, perioperative complications, length of stay, and hospitalization costs also were analyzed. Results: Of 1,324,083 hospitalizations across an annual average of 703 centres, 4.9% of patients received their operation at an HAC (annual average of 70 centres). Compared to non-HACs, HACs had a lower annual cardiac case volume (62 [interquartile range: 40-115] vs 145 [interquartile range: 80-265] cases; Conclusions: We demonstrated significant hospital-level variation in perioperative AKI. HACs were associated with inferior clinical outcomes and higher levels of resource utilization.

Identifiers

PMID40586015
PMCPMC12198644

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.