Evidence map›Paper›PMID 40586125›Full record

ArticleHuman brain mapping2025

Dynamic Functional Connectivity Between Amygdala and Cognitive Control Network Predicts Delay Discounting in Older Adolescents.

Attakias T Mertens, Callum Goldsmith, Derek J Pavelka, Jacob J Oleson, Gaelle E Doucet

Abstract read
In one paragraph

Article in Human brain mapping, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Attakias T MertensInstitute for Human Neuroscience, Omaha, Nebraska, USA.
Callum GoldsmithInstitute for Human Neuroscience, Omaha, Nebraska, USA.ORCID 0009-0006-6446-9803
Derek J PavelkaInstitute for Human Neuroscience, Omaha, Nebraska, USA.
Jacob J OlesonDepartment of Biostatistics - College of Public Health Building, University of Iowa, Iowa City, Iowa, USA.
Gaelle E DoucetInstitute for Human Neuroscience, Omaha, Nebraska, USA.ORCID 0000-0003-4120-0474

Funding

Stress-Induced Aberrations in the Mitochondrial Redox Environment Impact Developing Neural Circuits Supporting Cognitive ControlP20GM144641 · NIGMS · FATHER FLANAGAN'S BOYS' HOME · PI Giorgia Picci · 2022 to 2026
$15.1M
A new reference atlas of brain networks to investigate neuropsychiatric traits in adolescentsR03MH129365 · NIMH · FATHER FLANAGAN'S BOYS' HOME · PI DOUCET, GAELLE EVE · 2023 to 2024
$162k
NIGMS NIH HHS P20 GM144641NIGMS NIH HHS P20GM144641NIMH NIH HHS R03 MH129365NIMH NIH HHS R03MH129365
6 · The paper itself

Abstract

There is a spike in reward sensitivity during adolescence. Delay discounting involves subjective valuation of a reward in context of when it is gained. This study sought to assess if dynamic functional connectivity between the cognitive control network and the amygdala could predict delay discounting in adolescents and young adults. 448 participants were separated into three age groups, including younger and older adolescents and young adults. A sliding-window approach was used to calculate dynamic functional connectivity between the left/right amygdala and the cognitive control network. Hierarchical models were run for each age group to determine if dynamic functional connectivity could predict delay discounting behavior in two delayed amount conditions above and beyond age and sex. Results showed that dynamic functional connectivity between the left, but not the right, amygdala and cognitive control network significantly predicted delay discounting in the larger amount condition for older adolescents. No significant results were found for the smaller amount condition in older adolescents or either condition in younger adolescents or adults. Stronger dynamic functional connectivity indicated a preference for immediate rewards during a larger amount condition in older adolescents only.

Indexed as

AmygdalaDelay DiscountingExecutive FunctionAdolescentAdultAge FactorsBrain MappingFemaleHumansMagnetic Resonance ImagingMaleNeural PathwaysRewardYoung Adultadolescenceamygdaladelay discountingdynamic functional connectivityresting‐state fMRI

Identifiers

PMID40586125
PMCPMC12207320

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.