Evidence map›Paper›PMID 40586598›Full record

ArticlemSystems2025

Minimization of proteome reallocation explains metabolic transition in hierarchical utilization of carbon sources.

Zhihao Liu, Minghao Chen, Jingmin Hu, Yonghong Wang, Yu Chen

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in mSystems, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Sodium ion stress accelerates cell lysis inApplied and environmental microbiology · 2026
    Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Zhihao LiuState Key Laboratory of Bioreactor Engineering, East China University of Science and Technology, Shanghai, China.ORCID 0009-0003-9811-9658
Minghao ChenState Key Laboratory of Bioreactor Engineering, East China University of Science and Technology, Shanghai, China.
Jingmin HuState Key Laboratory of Bioreactor Engineering, East China University of Science and Technology, Shanghai, China.
Yonghong WangState Key Laboratory of Bioreactor Engineering, East China University of Science and Technology, Shanghai, China.ORCID 0000-0002-7619-9496
Yu ChenState Key Laboratory of Quantitative Synthetic Biology, Shenzhen Institute of Synthetic Biology, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, China.ORCID 0000-0003-3326-9068

Funding

National Key Research and Development Program of China 2024YFA0920300National Natural Science Foundation of China 21878084
6 · The paper itself

Abstract

Cells choose between alternative pathways in metabolic networks under diverse environmental conditions, but the principles governing the choice are insufficiently understood, especially in response to dynamically changing conditions. Here, we observed that the lactic acid bacterium

Indexed as

Bacillus coagulansBacterial ProteinsCarbonProteomeFermentationGlucoseMetabolic Networks and PathwaysModels, BiologicalTrehaloseBacterial ProteinsCarbonGlucoseProteomeTrehaloseenzyme constraintmetabolic modelmetabolic transitionmixed carbon sources

Identifiers

PMID40586598
PMCPMC12282068

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.