Evidence mapPaperPMID 40589031Full record

ReviewObesity reviews : an official journal of the International Association for the Study of Obesity2025

Weight Loss-Associated Remodeling of Adipose Tissue Immunometabolism.

Paulo José Basso, Alejandro Schcolnik-Cabrera, Mengyi Zhu, Erin Strachan, Xavier Clemente-Casares, Sue Tsai

Abstract readReview
In one paragraph

Review in Obesity reviews : an official journal of the International Association for the Study of Obesity, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Weight Loss-Associated Remodeling of Adipose Tissue Immunometabolism.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2025
    Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Paulo José BassoDepartment of Medical Microbiology & Immunology, University of Alberta, Edmonton, Canada.ORCID 0000-0003-4856-9207
Alejandro Schcolnik-CabreraDepartment of Medical Microbiology & Immunology, University of Alberta, Edmonton, Canada.ORCID 0000-0001-7734-3253
Mengyi ZhuDepartment of Medical Microbiology & Immunology, University of Alberta, Edmonton, Canada.ORCID 0000-0001-6307-5008
Erin StrachanDepartment of Medical Microbiology & Immunology, University of Alberta, Edmonton, Canada.ORCID 0000-0001-9804-8798
Xavier Clemente-CasaresDepartment of Medical Microbiology & Immunology, University of Alberta, Edmonton, Canada.ORCID 0000-0002-8627-4971
Sue TsaiDepartment of Medical Microbiology & Immunology, University of Alberta, Edmonton, Canada.ORCID 0000-0002-6261-5233

Funding

CIHR 202104PJT
6 · The paper itself

Abstract

Obesity is a multifactorial condition characterized by excessive adiposity and systemic chronic low-grade inflammation. Recent literature reflects a growing appreciation for the complex interplay between metabolism and the immune system in the pathogenesis of obesity-related health conditions. However, this field of investigation, also known as immunometabolism, requires more in-depth study to fully understand the impact of weight loss treatments on the metabolism and function of immune cells. Despite indications that weight loss can alleviate certain metabolic dysfunctions associated with obesity, the extent to which immunometabolic parameters return to baseline posttherapy remains largely unexplored. Therefore, this review intends to re-examine critical aspects of obesity pathophysiology and highlight recent advancements in literature regarding the effects of weight loss interventions on the metabolism and function of immune cells. Addressing this field is crucial for optimizing obesity management strategies and gaining insights into long-term metabolic health outcomes.

Indexed as

Adipose TissueObesityWeight LossHumansInflammationadipose tissue‐infiltrating immune cellsanti‐obesity medicationexercise/caloric restrictionmetabolism

Identifiers

PMID40589031
PMCPMC12620110

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.