Evidence map›Paper›PMID 40589137›Full record

ArticlePublic health nutrition2025

Associations between perinatal HIV-related risk factors and select serum PUFA levels among Ugandan children and adolescents.

Vanessa N Cardino, Selin Sergin, Sarah K Zalwango, Jenifer I Fenton, Amara E Ezeamama

Abstract read
In one paragraph

Article in Public health nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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No citing paper in PubMed yet.

4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Vanessa N CardinoDepartment of Food Science and Human Nutrition, Michigan State University, 469 Wilson Road, East Lansing, MI48824, USA.
Selin SerginDepartment of Food Science and Human Nutrition, Michigan State University, 469 Wilson Road, East Lansing, MI48824, USA.
Sarah K ZalwangoKampala Capital City Authority, City Hall, Plot 1-3, Apollo Kaggwa Road PO BOX 7010 Kampala, Uganda.
Jenifer I FentonDepartment of Food Science and Human Nutrition, Michigan State University, 469 Wilson Road, East Lansing, MI48824, USA.ORCID 0000-0002-8875-3239
Amara E EzeamamaDepartment of Psychiatry, Michigan State University, 909 Wilson Road, East Lansing, MI48824, USA.

Funding

Identifying Adolescents at High Risk of Neurocognitive Disorder: Development and Validation of a Composite Risk IndexR01NS122510 · NINDS · MICHIGAN STATE UNIVERSITY · PI EZEAMAMA, AMARA E · 2020 to 2023
$3.1M
Perinatal HIV infection/exposure, stress and long-term functional survival in Ugandan adolescentsR21HD088169 · NICHD · MICHIGAN STATE UNIVERSITY · PI EZEAMAMA, AMARA E · 2017 to 2018
$696k
NICHD NIH HHS R21 HD088169NINDS NIH HHS R01 NS122510
6 · The paper itself

Abstract

objectiveTo (1) determine how serum fatty acid (FA) levels differ by developmental stage, (2) quantify associations between perinatal HIV-related factors and PUFA levels and (3) examine the heterogeneity of these associations by developmental stage.

designCross-sectional secondary analysis of baseline data from two prospective cohorts.

settingKampala, Uganda.

participants243 children (6-10 years old) and 383 adolescents (11-18 years old) were recruited at Kawaala Health Center based on perinatal HIV status. Youth (children and adolescents) were classified as: those with perinatal HIV infection (PHIV:

resultsAdolescents had lower

conclusionIn this sample, perinatal HIV status was associated with low PUFA levels, and these associations varied by developmental stage and IPA exposure type. Future research should elucidate the contribution of IPA exposure type to EFAD and the implications of these differences on growth and cognitive development.

Indexed as

Fatty Acids, UnsaturatedHIV InfectionsInfectious Disease Transmission, VerticalAdolescentChildCross-Sectional StudiesFatty Acids, Omega-3Fatty Acids, Omega-6FemaleHumansMalePregnancyProspective StudiesRisk FactorsUgandaFatty Acids, Omega-3Fatty Acids, Omega-6Fatty Acids, UnsaturatedAntiretroviral therapyChildrenHIVPUFAUganda

Identifiers

PMID40589137
PMCPMC12392348

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.