ArticleLangenbeck's archives of surgery2025
Elevated prealbumin levels after preoperative nutritional intervention is an independent prognostic factor for overall survival after radical gastrectomy in patients with gastric cancer and severe malnutrition.
Article in Langenbeck's archives of surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThis study aimed to clarify the effects of preoperative nutritional intervention on long-term survival after radical gastrectomy in patients with severe malnutrition.
methodsThis retrospective cohort study included consecutive patients who underwent radical gastrectomy for primary stages I-III gastric cancer between August 2010 and December 2021. The primary outcome measure was overall survival (OS). We compared OS between the groups with and without nutritional intervention. In the intervention group, we compared OS between the groups with and without nutritional improvement. Prognostic factors were identified using the Cox proportional hazards regression analysis.
resultsMedian follow-up duration was 51 months. Of the 118 patients, 35 (29.7%) and 83 (70.3%) were in the group without and with nutritional intervention, respectively. Of the 83 patients in the group with nutritional intervention, 24 (28.9%) were classified as group without elevated prealbumin levels and 59 (71.1%) as group with elevated prealbumin levels. There was no difference in OS between the groups with and without nutritional intervention (P = 0.532); however, there was a trend toward better OS in the group with elevated prealbumin levels than in the group without elevated prealbumin levels (P = 0.181). Multivariate analysis showed that elevated prealbumin levels after intervention was an independent, favorable, prognostic factor for OS (hazard ratio, 0.320; 95% confidence interval, 0.112-0.917; P = 0.030).
conclusionsPreoperative nutritional therapy in patients with severe malnutrition does not contribute to long-term survival after gastrectomy. However, in patients who have undergone nutritional therapy, prognosis could be predicted by elevated prealbumin levels.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.