Evidence map›Paper›PMID 40593196›Full record

Trial reportScientific reports2025

Predictors of fatigue improvement in multimodal, multimodal-aerobic and aerobic exercise intervention studies in breast cancer survivors with cancer-related fatigue.

M Kröz, M Reif, L R Fässler-Teal, B Berger, C Sasselli, R Zerm, D Martin, C Gutenbrunner, A Büssing

Erratum issuedAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors.

M KrözResearch Institute Havelhöhe, Berlin, Germany.
M ReifSociety for Clinical Research, Berlin, Germany.
L R Fässler-TealResearch Department and Sleep Medicine, Klinik Arlesheim, Arlesheim, Switzerland. lorna.faessler@klinik-arlesheim.ch.
B BergerInstitute of Integrative Medicine, University of Witten/Herdecke, Witten/Herdecke, Germany.
C SasselliResearch Department and Sleep Medicine, Klinik Arlesheim, Arlesheim, Switzerland.
R ZermResearch Institute Havelhöhe, Berlin, Germany.
D MartinInstitute of Integrative Medicine, University of Witten/Herdecke, Witten/Herdecke, Germany.
C GutenbrunnerClinic for Rehabilitative Medicine, Hannover Medical School, Hannover, Germany.
A BüssingInstitute of Integrative Medicine, University of Witten/Herdecke, Witten/Herdecke, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cancer-related fatigue (CRF) is common among breast cancer (BC) survivors. In addition to aerobic training, psychoeducation, sleep education/restriction, and mindfulness-based therapies are shown to reduce CRF. This study investigates the predictive effect of hygiogenetic and salutogenetic concepts, such as autonomic regulation (aR), self-regulation (SRS) and internal coherence (ICS) along with sleep quality (PSQI) and quality of life (EORTC QLQ C30, including cognitive, emotional and physical functioning) on the success of CRF therapies. Two studies are analyzed: a pilot (CRF-1) with 36 BC patients and a follow-up study (CRF2) with 126 patients either randomized or assigned to therapy by preference. All parameters were assessed at baseline and 10 weeks post-intervention (T1), and in CRF-2 also six months later (T2), and after four years (T3). Multiple linear regression models were applied. Trait aR and ICS are shown to be significant predictors of CRF when all timepoints of the CRF-2 study are included (β

Indexed as

Breast NeoplasmsCancer SurvivorsExerciseExercise TherapyFatigueAdultAgedFemaleHumansMiddle AgedPilot ProjectsQuality of LifeSleep QualityAutonomic regulationBreast cancerCancer-related fatigueInternal coherence scaleMultimodal therapySalutogenesis

Identifiers

PMID40593196
PMCPMC12218493

What Socratic holds

Textmetadata
LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.