Evidence map›Paper›PMID 40594621›Full record

ArticleScientific reports2025

Enrofloxacin exposure enhances GABA synthesis via PI3K/Akt signaling pathway in crucian carp brain.

Jiming Ruan, Gen Wan, Ping Luo, Jianzhen Huang, Huazhong Liu

Abstract read
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jiming RuanCollege of Animal Science & Technology, Jiangxi Agricultural University, Nanchang, 330045, People's Republic of China.
Gen WanCollege of Animal Science & Technology, Jiangxi Agricultural University, Nanchang, 330045, People's Republic of China.
Ping LuoCollege of Chemistry & Environmental Science, Guangdong Ocean University, Zhanjiang, 524088, People's Republic of China.
Jianzhen HuangCollege of Animal Science & Technology, Jiangxi Agricultural University, Nanchang, 330045, People's Republic of China.
Huazhong LiuCollege of Chemistry & Environmental Science, Guangdong Ocean University, Zhanjiang, 524088, People's Republic of China. liuhzbs@163.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

It has been proved that enrofloxacin (ENR) induces disturbance of neuroendocrine system, resulting in reproductive damage in animals and fish. Our previous work revealed that ENR promoted testosterone (T) synthesis but inhibited the conversion of T to E

Indexed as

BrainCarpsEnrofloxacingamma-Aminobutyric AcidPhosphatidylinositol 3-KinasesProto-Oncogene Proteins c-aktSignal Transduction4-Aminobutyrate TransaminaseAnimalsFemaleGlutamate Decarboxylase4-Aminobutyrate TransaminaseEnrofloxacingamma-Aminobutyric AcidGlutamate DecarboxylasePhosphatidylinositol 3-KinasesProto-Oncogene Proteins c-aktEnrofloxacinFemale crucian carpGABAPI3K/Akt

Identifiers

PMID40594621
PMCPMC12216971

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.