Evidence map›Paper›PMID 40594863›Full record

ArticleScientific reports2025

The effects of systemic and sustained hypoxia on orthodontic tooth movement in rats.

Kwanrat Ploysongsang, Yukiho Kobayashi, Yeming Lu, Yuki Niki, Janeta Chavanavesh, Keiji Moriyama

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Kwanrat PloysongsangDepartment of Maxillofacial Orthognathics, Division of Maxillofacial and Neck Reconstruction, Graduate School of Medical and Dental Sciences, Institute of Science Tokyo, 1-5-45 Yushima, Bunkyo-ku, Tokyo, 113-8549, Japan.
Yukiho KobayashiDepartment of Maxillofacial Orthognathics, Division of Maxillofacial and Neck Reconstruction, Graduate School of Medical and Dental Sciences, Institute of Science Tokyo, 1-5-45 Yushima, Bunkyo-ku, Tokyo, 113-8549, Japan. yukimort@tmd.ac.jp.
Yeming LuDepartment of Maxillofacial Orthognathics, Division of Maxillofacial and Neck Reconstruction, Graduate School of Medical and Dental Sciences, Institute of Science Tokyo, 1-5-45 Yushima, Bunkyo-ku, Tokyo, 113-8549, Japan.
Yuki NikiDepartment of Maxillofacial Orthognathics, Division of Maxillofacial and Neck Reconstruction, Graduate School of Medical and Dental Sciences, Institute of Science Tokyo, 1-5-45 Yushima, Bunkyo-ku, Tokyo, 113-8549, Japan.
Janeta ChavanaveshDepartment of Orthodontics, Faculty of Dentistry, Chulalongkorn University, Bangkok, 10330, Thailand.
Keiji MoriyamaDepartment of Maxillofacial Orthognathics, Division of Maxillofacial and Neck Reconstruction, Graduate School of Medical and Dental Sciences, Institute of Science Tokyo, 1-5-45 Yushima, Bunkyo-ku, Tokyo, 113-8549, Japan.

Funding

Japan Society for the Promotion of Science JP 23K27800
6 · The paper itself

Abstract

During orthodontic tooth movement (OTM), local hypoxia on the compression side stimulates cellular remodelling of periodontal tissues. We investigated the effects of systemic, sustained hypoxia on OTM in vivo. OTM was performed on the right maxillary first molar (M1) of 8-week-old male Sprague-Dawley rats using a 10-gf nickel-titanium closed-coil spring for 4 weeks under control (21% O

Indexed as

HypoxiaTooth Movement TechniquesAlveolar ProcessAnimalsCell DifferentiationCell ProliferationCore Binding Factor Alpha 1 SubunitMaleMolarOsteoclastsPeriodontal LigamentRatsRats, Sprague-DawleyVascular Endothelial Growth Factor AX-Ray MicrotomographyCore Binding Factor Alpha 1 SubunitRunx2 protein, ratVascular Endothelial Growth Factor AHypoxiaOrthodontic tooth movementOsteoblastOsteoclastPeriodontal ligament

Identifiers

PMID40594863
PMCPMC12219902

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.