Evidence map›Paper›PMID 40595076›Full record

ArticleScientific reports2025

Predictive effect and clinical diagnosis significance of exosome-related genes for nonalcoholic fatty liver disease-related hepatocellular carcinoma.

Xiaoqian Ding, Ling Li, Keqing Feng, Jie Zhang, Baokai Sun, Xueru Chu, Qi Zhang, Likun Zhuang

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Xiaoqian DingSchool of Medicine and Pharmacy, Ocean University of China, Qingdao, China.
Ling LiDepartment of healthcare-associated infection management, Qingdao Municipal Hospital, Qingdao University, Qingdao, 266071, China.
Keqing FengSchool of Medicine and Pharmacy, Ocean University of China, Qingdao, China.
Jie ZhangDepartment of Infectious Diseases, Qingdao Municipal Hospital, Qingdao University, Qingdao, 266071, China.
Baokai SunDepartment of Infectious Diseases, Qingdao Municipal Hospital, Qingdao University, Qingdao, 266071, China.
Xueru ChuSchool of Medicine and Pharmacy, Ocean University of China, Qingdao, China.
Qi ZhangQingdao Municipal Hospital, Central Laboratories, Qingdao University, Qingdao, 266071, China. zq199305@163.com.
Likun ZhuangQingdao Municipal Hospital, Central Laboratories, Qingdao University, Qingdao, 266071, China. zlk0823@163.com.

Funding

National Natural Science Foundation of China 81873976
6 · The paper itself

Abstract

Nonalcoholic fatty liver disease (NAFLD) is a multifactorial metabolic syndrome which could develop into hepatocellular carcinoma (HCC). Exosomes could mediate intercellular communications and play key roles in the occurrence and development of many diseases including NAFLD and HCC. However, expressions and roles of the genes related to exosomes in NAFLD-related HCC remain unclear. The objective of this study was to investigate the expressions and diagnostic values of exosome-related genes in NAFLD-related HCC. Firstly, two risk subgroups of patients with NAFLD-related HCC from the gene expression omnibus (GEO) database were identified based on exosome-related genes. High levels of memory CD4

Indexed as

Carcinoma, HepatocellularExosomesLiver NeoplasmsNon-alcoholic Fatty Liver DiseaseAnimalsBiomarkers, TumorCD4-Positive T-LymphocytesFemaleGene Expression ProfilingGene Expression Regulation, NeoplasticHumansMaleMiceROC CurveBiomarkers, TumorClinical diagnosisExosome-related genesNonalcoholic fatty liver disease-related hepatocellular carcinomaPredictive formulaPrognosis

Identifiers

PMID40595076
PMCPMC12215628

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.