Evidence map›Paper›PMID 40596952›Full record

ArticleBMC infectious diseases2025

Helicobacter pylori infection increases the risk of dyslipidemia in Chinese non-obese and non-diabetic population from the perspective of age category: a retrospective cross-sectional study.

Huihui Shang, Jiawei Wang, Xinya Zhang, Dingli Zhang, Kai Yue, Song Xu

Abstract read
In one paragraph

Article in BMC infectious diseases, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Microorganisms · 2025
    Article
4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Huihui ShangDepartment of Health Medicine, The 991 st Hospital of Joint Logistic Support Force of People's Liberation Army, Xiangyang, 441000, Hubei, China.
Jiawei WangDepartment of Medical Service Office, The 991 st Hospital of Joint Logistic Support Force of People's Liberation Army, Xiangyang, 441000, Hubei, China.
Xinya ZhangDepartment of Health Medicine, The 991 st Hospital of Joint Logistic Support Force of People's Liberation Army, Xiangyang, 441000, Hubei, China.
Dingli ZhangDepartment of Neurology, The 991 st Hospital of Joint Logistic Support Force of People's Liberation Army, Xiangyang, 441000, Hubei, China.
Kai YueDepartment of Medical engineering, The 991 st Hospital of Joint Logistic Support Force of People's Liberation Army, Xiangyang, 441000, Hubei, China. 397374436@qq.com.
Song XuDepartment of Psychiatry, The 991 st Hospital of Joint Logistic Support Force of People's Liberation Army, Xi angyang, 441000, Hubei, China. 99043339@qq.com.

Funding

The 991 st Hospital of Joint Logistic Support Force of People's Liberation Army 991YJ-202316
6 · The paper itself

Abstract

BACKGROUND/

objectivesCurrently, the increased prevalence of Helicobacter pylori (H. pylori) infection and elevated levels of dyslipidemia pose a major public health challenge. We aimed to investigate the association between dyslipidemia and H. pylori infection from the perspective of age category.

methodsA retrospective cross-sectional study was conducted on 3530 non-obese and non-diabetic individuals who underwent a physical examination at the 991st Hospital of the Joint Logistics Support Force of People's Liberation Army from January to December 2024. Physical measurements, hematological markers, and detection of H. pylori were gathered from all patients. According to the results of the detection of H. pylori, the subjects were divided into the H. pylori-positive group and the H. pylori-negative group. The correlation between H. pylori infection and blood lipid levels was compared between the two groups according to age category. Binary Logistic regression analysis was used to analyze the factors influencing H. pylori infection.

resultsAmong 3530 healthy subjects, 1176 cases (33.31%) were in the H. pylori-positive group and 2354 cases (66.69%) were in the H. pylori-negative group. In the 30-59 age group, low-density lipoprotein cholesterol (LDL-c), triglycerides (TG), and total cholesterol (TC) levels were significantly higher in H. pylori-positive individuals compared to H. pylori-negative individuals (P < 0.05), with no significant differences in other age groups (P > 0.05). Binary Logistic regression showed that H. pylori infection was associated with elevated LDL-c [OR = 2.100, 95%CI (1.771-2.491), P < 0.001], elevated TC [OR = 2.844, 95%CI (2.232-3.623), P < 0.001], male gender [OR = 1.267, 95%CI (1.054-1.524), P < 0.05], ages 40-49 [OR = 1.602, 95%CI (1.181-2.173), P < 0.05].

conclusionsH. pylori infection is associated with dyslipidemia in non-obese and non-diabetic people, especially those aged 30-59. In men aged 40-49, H. pylori positivity was more strongly related to elevated TC and LDL-c, highlighting the importance of routine H. pylori screening in this age group.

Indexed as

DyslipidemiasHelicobacter InfectionsHelicobacter pyloriAdultAgedAge FactorsChinaCross-Sectional StudiesEast Asian PeopleFemaleHumansMaleMiddle AgedPrevalenceRetrospective StudiesRisk FactorsDyslipidemiaHelicobacter pyloriLow-density lipoprotein cholesterolTotal cholesterolTriglyceride

Identifiers

PMID40596952
PMCPMC12211879

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.