Evidence map›Paper›PMID 40597422›Full record

ArticleBMC research notes2025

Short-term effects of Ahmed valve implantation on ocular biometry and corneal biomechanics in neovascular glaucoma.

Ali Azimi, Alireza Attar, Aidin Meshksar, Hooman Razmi, Mohammad Hassan Jalalpour, Amirmohammad Fathian, Adele Yarmohammadi

Abstract read
In one paragraph

Article in BMC research notes, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

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No citing paper in PubMed yet.

4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Ali AzimiDepartment of Ophthalmology, Poostchi Ophthalmology Research Center, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran.
Alireza AttarDepartment of Ophthalmology, Poostchi Ophthalmology Research Center, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran. Alireza.attar8374@gmail.com.
Aidin MeshksarDepartment of Ophthalmology, Poostchi Ophthalmology Research Center, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran.
Hooman RazmiDepartment of Ophthalmology, Poostchi Ophthalmology Research Center, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran.
Mohammad Hassan JalalpourDepartment of Ophthalmology, Poostchi Ophthalmology Research Center, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran.
Amirmohammad FathianDepartment of Ophthalmology, Poostchi Ophthalmology Research Center, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran.
Adele YarmohammadiUC San Diego Shiley Eye Institute, San Diego, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo evaluate the impact of Ahmed glaucoma valve (AGV) implantation on ocular biometric and corneal biomechanical parameters in patients with neovascular glaucoma (NVG), with the goal of understanding how these changes influence intraocular pressure (IOP) control, surgical outcomes, and long-term prognosis.

resultsEighteen NVG patients (mean age: 57.44 ± 10.33 years) underwent AGV implantation. A significant reduction in IOP was observed, from 36.65 ± 12.3 mmHg preoperatively to 15.5 ± 2.64 mmHg postoperatively (p < 0.001). Axial length decreased from 23.42 ± 0.76 mm to 23.21 ± 0.76 mm (p < 0.001), while anterior chamber depth increased significantly (p = 0.037). Both corneal keratometry and central corneal thickness showed significant postoperative decreases (p < 0.001). Corneal biomechanical parameters such as peak distance and deformation amplitude increased significantly (p = 0.004 and p = 0.001, respectively), whereas no significant changes were noted in applanation lengths and velocities (p > 0.05). These findings suggest that AGV implantation leads to substantial alterations in ocular structure and biomechanics, which may contribute to improved clinical outcomes in NVG management.

Indexed as

CorneaGlaucoma Drainage ImplantsGlaucoma, NeovascularAdultAgedBiomechanical PhenomenaBiometryFemaleHumansIntraocular PressureMaleMiddle AgedTreatment OutcomeAhmed glaucoma valve implantationCorneal biomechanicalNeovascular glaucoma

Identifiers

PMID40597422
PMCPMC12217899

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.