Evidence map›Paper›PMID 40598250›Full record

ReviewChinese medicine2025

Traditional Chinese medicine in diabetic kidney disease: multifaceted therapeutic mechanisms and research progress.

Rushuang Cai, Chunying Li, Yong Zhao, Haisheng Yuan, Xiaomeng Zhang, Aihua Liang, Yan Yi

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Chinese medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Rushuang CaiState Key Laboratory for Quality Ensurance and Sustainable use of Dao-Di Herbs, Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing, 100700, China.
Chunying LiState Key Laboratory for Quality Ensurance and Sustainable use of Dao-Di Herbs, Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing, 100700, China.
Yong ZhaoState Key Laboratory for Quality Ensurance and Sustainable use of Dao-Di Herbs, Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing, 100700, China.
Haisheng YuanState Key Laboratory for Quality Ensurance and Sustainable use of Dao-Di Herbs, Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing, 100700, China.
Xiaomeng ZhangState Key Laboratory for Quality Ensurance and Sustainable use of Dao-Di Herbs, Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing, 100700, China.
Aihua LiangState Key Laboratory for Quality Ensurance and Sustainable use of Dao-Di Herbs, Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing, 100700, China. ahliang@icmm.ac.cn.
Yan YiState Key Laboratory for Quality Ensurance and Sustainable use of Dao-Di Herbs, Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing, 100700, China. yyi@icmm.ac.cn.ORCID http://orcid.org/0000-0003-3405-2987

Funding

Innovation Fund of the China Association of Chinese Medicine CI2023C006YGLiaoning Science and Technology Plan Project 2023JH1/10400029National Natural Science Foundation of China 82192913State Key Laboratory Breeding Base for Zhejiang Sustainable Pest and Disease Control ZG2024001-03
6 · The paper itself

Abstract

Diabetic kidney disease (DKD) is a severe complication of diabetes and a leading cause of end-stage renal disease (ESRD). It is characterized by a complex pathogenesis that involves genetic, epigenetic, metabolic, and multifactorial elements. Current therapeutic approaches for DKD have significant limitations. In contrast, Traditional Chinese Medicine (TCM), with its personalized treatment based on syndrome differentiation, shows potential to modulate multiple pathological pathways implicated in DKD. This review provides a detailed examination of DKD pathogenesis and the progress in TCM research, offering valuable insights for DKD treatment research and clinical practice.

Indexed as

Diabetic kidney diseasePharmacological mechanismTraditional Chinese medicine

Identifiers

PMID40598250
PMCPMC12211247

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.