Trial reportBMC medicine2025
Effectiveness of the WeChat-based mini-program ("Sober Time ACT") on individuals with hazardous drinking in China: a randomized controlled trial.
Trial report in BMC medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05827822 (Effectiveness of a WeChat-based Alcohol Consumption Intervention Mini-program), which is not on this map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Effectiveness of a WeChat-based Alcohol Consumption Intervention Mini-program ("Sober Time ACT") Among Hazardous and Problematic Drinkers in China
Who cites it
1 citing paper in PubMed.
- Article
Corrections and comments
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Authors and funding
7 authors.
Funding
Abstract
backgroundHazardous drinking is a big problem in China, but there are no effective intervention measures to solve this issue. This study aimed to evaluate the effectiveness of the WeChat-based mini-program "Sober Time ACT" in the hazardous drinking population.
methodsA prospective two-arm randomized controlled trial (RCT) was conducted via WeChat between March and November 2023. A total of 186 participants with hazardous drinking were included and randomized in a 1:1 ratio. The intervention group (n = 93) received the "Sober Time ACT" program, and the control group (n = 93) received alcohol abstinence brochures for 4 weeks. The primary outcome measure was the change in craving before and after the intervention. Secondary outcomes included changes in average weekly alcohol consumption and average number of risky drinking days per month, as well as psychological indicators (depression, anxiety, sleep status, and perceived stress). Intention-to-treat (ITT) analyses were applied. Sensitivity analysis was conducted using the expectation-maximization (EM) and the multiple imputation (MI) methods to handle missing data. Repeated measures ANOVA and linear regression models were used to evaluate all outcome indicators.
resultsThe analysis revealed statistically significant time-by-group interaction effects for alcohol craving (P = 0.01), average weekly alcohol consumption (P = 0.03), anxiety levels (P = 0.03) and perceived stress (P < 0.05). The intervention group showed a significantly greater reduction in cravings from baseline to the end of follow-up compared to the control group with a group difference (P = 0.02 for EM and P = 0.01 for MI).
conclusionsThese findings provide preliminary prospective evidence that, despite the limitation of high dropout rate, the "Sober Time ACT" mini-program not only effectively reduces alcohol craving and consumption but also improves related psychological indicators to a certain extent, providing an innovative and effective intervention tool for addressing hazardous drinking in China.
trial registrationThe study was registered on ClinicalTrials.gov (NCT05827822) in March 2023.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.