ArticleiScience2025
A simple score, CKM
Article in iScience, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
6 citing papers in PubMed.
- A machine learning-derived aging index for risk stratification and mortality prediction in cardiovascular-kidney-metabolic syndrome: A retrospective cohort study.PLoS medicine · 2026Article
- Metoprolol Population Pharmacokinetics in Older Chinese Patients With CKM Syndrome: Joint Effects of rs1065852 and CKMClinical and translational science · 2026Article
- Development and validation of continuous cardiovascular-kidney-metabolic syndrome severity score (cCKMS-S) complementing CKM staging.Lipids in health and disease · 2026Article
- Brain age gap as biomarker linking cardiovascular diseases genetic susceptibility and causality.iScience · 2026Article
- The C-reactive protein-triglyceride glucose index (CTI) predicts mortality in cardiovascular-kidney-metabolic syndrome: a dual-cohort study with machine learning validation.International journal of surgery (London, England) · 2026Article
- Evaluation, Management and Therapeutic Approach of Cardiovascular-Kidney-Metabolic Syndrome: A Multidisciplinary Delphi Expert Consensus.Journal of clinical medicine · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
15 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The 2023 American Heart Association (AHA) Health Presidential Advisory recommends risk assessment of cardiovascular disease (CVD) within the context of Cardiovascular-Kidney-Metabolic syndrome (CKMS). However, an intuitive and easy-to-use risk score incorporating CKM health metrics remains needed to prevent CVD in daily practice. We constructed an acronym-based clinical risk score using CKM-related predictors and externally validated its predictive performance for total CVD and its subtypes of atherosclerotic CVD and heart failure, based on two prospective community-based cohorts. We found the Cholesterol, Kidney function, Male [Doubled], Smoker [Doubled]-Blood pressure, Age, and fast blood Glucose (CKM
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.