Evidence map›Paper›PMID 40599337›Full record

ArticleJournal of the Endocrine Society2025

Prevalence of MASLD in People With Diabetes Has Decreased in the US, but Rates of Liver Fibrosis Are Still on the Rise.

Fernando Bril, Parameshwara Bolla, Ky Huynh, Sumedha Bobba

Abstract read
In one paragraph

Article in Journal of the Endocrine Society, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Review
  9. Clinical and experimental gastroenterology · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Fernando BrilDivision of Endocrinology, Diabetes and Metabolism, Department of Medicine, University of Alabama at Birmingham, Birmingham, AL 35205, USA.ORCID https://orcid.org/0000-0001-5570-4396
Parameshwara BollaDivision of Endocrinology, Diabetes and Metabolism, Department of Medicine, University of Alabama at Birmingham, Birmingham, AL 35205, USA.
Ky HuynhDivision of Endocrinology, Diabetes and Metabolism, Department of Medicine, University of Alabama at Birmingham, Birmingham, AL 35205, USA.
Sumedha BobbaUniversity of Alabama at Birmingham Heersink School of Medicine, Birmingham, AL 35205, USA.ORCID https://orcid.org/0009-0000-4180-1064

Funding

University of Alabama at Birmingham's Diabetes Research CenterP30DK079626 · NIDDK · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI Kirk Michael Habegger · 2013 to 2026
$19.5M
NIDDK NIH HHS P30 DK079626
6 · The paper itself

Abstract

Objective: We aimed to evaluate recent changes in the prevalence of steatotic liver disease, its subtypes, and liver fibrosis among US adults with and without diabetes between 2017-2020 and 2021-2023. Research Design and Methods: In this serial cross-sectional study, we assessed adults aged ≥18 years with complete vibration-controlled transient elastography (Fibroscan®) data from the National Health and Nutrition Examination Surveys from 2017-2020 and 2021-2023. Metabolic dysfunction-associated steatotic liver disease (MASLD) was defined as liver steatosis in the presence of 1 cardiometabolic risk factor. Results: A total of 13 153 adults (n = 7683 from 2017-2020; n = 5470 from 2021-2023) were included. The prevalence of MASLD significantly decreased from 37.6% to 32.5% in this period ( Conclusion: Despite the evidence of a decline in MASLD prevalence, rates of liver fibrosis and cirrhosis are rising, especially in individuals with diabetes. This underscores the need for improved screening of liver fibrosis, early initiation of effective pharmacological therapies, and aggressive management of related cardiometabolic conditions in individuals with diabetes.

Indexed as

cirrhosisliver fatNAFLDNASHobesity

Identifiers

PMID40599337
PMCPMC12210375

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.