Evidence map›Paper›PMID 40599492›Full record

ArticleOpen forum infectious diseases2025

Retrospective Analysis of Severe Fever With Thrombocytopenia Syndrome and Construction of a Nomogram Prediction Model for Mortality Risk Factors.

Gang Chen, Yuchen Du, Xiuchang Ma, Yaowen Liang, Apeng Chen, Jie Wei, Jinhuan Wu, Wenxian Qian, Shuqin Xie, Yi Yan and 4 more

Abstract read
In one paragraph

Article in Open forum infectious diseases, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Gang ChenDepartment of Pediatrics, The First People's Hospital of Lianyungang, Xuzhou Medical University Affiliated Hospital of Lianyungang (Lianyungang Clinical College of Nanjing Medical University), Lianyungang, China.
Yuchen DuThe Second Hospital of Nanjing, Affiliated Hospital to Nanjing University of Chinese Medicine, Nanjing, China.
Xiuchang MaThe Second Hospital of Nanjing, Affiliated Hospital to Nanjing University of Chinese Medicine, Nanjing, China.
Yaowen LiangThe Second Hospital of Nanjing, Affiliated Hospital to Nanjing University of Chinese Medicine, Nanjing, China.
Apeng ChenChildren's Hospital of Nanjing Medical University, Nanjing, China.ORCID https://orcid.org/0000-0002-1936-2007
Jie WeiThe Second Hospital of Nanjing, Affiliated Hospital to Nanjing University of Chinese Medicine, Nanjing, China.
Jinhuan WuChildren's Hospital of Nanjing Medical University, Nanjing, China.
Wenxian QianThe Second Hospital of Nanjing, Affiliated Hospital to Nanjing University of Chinese Medicine, Nanjing, China.
Shuqin XieChildren's Hospital of Nanjing Medical University, Nanjing, China.
Yi YanChildren's Hospital of Nanjing Medical University, Nanjing, China.
Zheng HuThe Second Hospital of Nanjing, Affiliated Hospital to Nanjing University of Chinese Medicine, Nanjing, China.
Yishan ZhengThe Second Hospital of Nanjing, Affiliated Hospital to Nanjing University of Chinese Medicine, Nanjing, China.
Man TianChildren's Hospital of Nanjing Medical University, Nanjing, China.
Changhua YiThe Second Hospital of Nanjing, Affiliated Hospital to Nanjing University of Chinese Medicine, Nanjing, China.ORCID https://orcid.org/0009-0008-2154-1662

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Severe fever with thrombocytopenia syndrome (SFTS) is an emerging zoonotic infectious disease caused by the SFTS virus and is characterized by a high mortality rate. The primary objective of this study was to investigate high-mortality risk factors in SFTS and to create a nomogram model for personalized prediction. Methods: A total of 523 patients with SFTS who were admitted to the Second Hospital of Nanjing, Nanjing University of Chinese Medicine, between January 2020 and December 2023 were retrospectively analyzed: 75 cases were classified in the death group and 448 cases in the survival group. Development of a predictive nomogram model was based on the independent risk factors that were stepwise screened through univariate analysis, LASSO analysis (least absolute shrinkage and selection operator), and multivariate logistic regression analysis. Results: Based on stepwise variable screening by univariate analysis, LASSO analysis, and multivariate logistic regression, the following were independent mortality risk factors in patients with SFTS: age (odds ratio [OR], 1.06; 95% CI, 1.03-1.10; Conclusions: A nomogram model consisting of 7 risk factors was successfully constructed, which can be used to predict SFTS mortality risk factors early.

Indexed as

epidemiologicalnomogram prediction modelretrospective analysisrisk factorsSFTS

Identifiers

PMID40599492
PMCPMC12207972

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.