Evidence map›Paper›PMID 40599782›Full record

ArticleFrontiers in immunology2025

Highly differentiated T cells link systemic and vascular inflammation in a mouse model of recurrent psoriasis.

Fabio Casciano, Paolo Severi, Laura Marongiu, Anna Caproni, Chiara Terranova, Alex Spitilli, Davide Ferrari, Chiara Ruzza, Peggy Marconi, Paola Rizzo and 3 more

Abstract read
In one paragraph

Article in Frontiers in immunology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Review
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Fabio CascianoDepartment of Environmental and Prevention Sciences and LTTA Centre, University of Ferrara, Ferrara, Italy.
Paolo SeveriDepartment of Translational Medicine, University of Ferrara, Ferrara, Italy.
Laura MarongiuDepartment of Biotechnology and Biosciences, University of Milano-Bicocca, Milan, Italy.
Anna CaproniDepartment of Environmental and Prevention Sciences and LTTA Centre, University of Ferrara, Ferrara, Italy.
Chiara TerranovaDepartment of Translational Medicine, University of Ferrara, Ferrara, Italy.
Alex SpitilliDepartment of Translational Medicine, University of Ferrara, Ferrara, Italy.
Davide FerrariDepartment of Life Sciences and Biotechnology, University of Ferrara, Ferrara, Italy.
Chiara RuzzaDepartment of Neurosciences and Rehabilitation, University of Ferrara, Ferrara, Italy.
Peggy MarconiDepartment of Environmental and Prevention Sciences and LTTA Centre, University of Ferrara, Ferrara, Italy.
Paola RizzoDepartment of Translational Medicine and LTTA Centre, University of Ferrara, Ferrara, Italy.
Francesca GranucciDepartment of Biotechnology and Biosciences, University of Milano-Bicocca, Milan, Italy.
Paola SecchieroDepartment of Translational Medicine, University of Ferrara, Ferrara, Italy.
Eva RealiDepartment of Translational Medicine, University of Ferrara, Ferrara, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Psoriasis is a chronic inflammatory skin-disease associated with cardiovascular comorbidities. In patients, T cells with a skin-primed phenotype are expanded in peripheral blood, indicating a role for skin to blood T cell recirculation in the development of systemic comorbidities. Here, we aimed to investigate (i) the establishment of CD4

Indexed as

CD4-Positive T-LymphocytesCD8-Positive T-LymphocytesCell DifferentiationPsoriasisVasculitisAnimalsDisease Models, AnimalFemaleHumansImmunologic MemoryInflammationLymphocyte ActivationMaleMemory T CellsMiceMice, Inbred C57BLcardiovascular comorbiditiesendothelial dysfunctionmouse model of recurrent psoriasisT cellsvascular inflammation

Identifiers

PMID40599782
PMCPMC12208849

What Socratic holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.