ArticlePleura and peritoneum2025
Visceral adipose tissue is associated with occult synchronous peritoneal metastasis in colorectal cancer.
Article in Pleura and peritoneum, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Development and external validation of a preoperative CT body composition-based model for predicting postoperative metastasis in colorectal cancer: a multicenter retrospective cohort study.Abdominal radiology (New York) · 2026Article
- Association of preoperative CT-derived visceral adipose tissue index with synchronous metastasis and metastasis-free survival after curative-intent surgery in colorectal cancer.Frontiers in oncology · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objectives: Synchronous peritoneal metastasis (PM) represents an advanced stage of colorectal cancer (CRC), indicating extensive tumor spread. Visceral adipose tissue (VAT) has been linked to cancer development and progression. This study aims to explore the relationship between VAT and occult synchronous PM in CRC patients before surgery. Methods: We enrolled 681 CRC patients, with 419 in the primary cohort (356 non-metastatic and 63 with PM) and 262 in the validation cohort (239 non-metastatic and 23 with PM). Clinical characteristics and laboratory measurements were collected prior to surgery. Adipose and muscle tissues were delineated on preoperative contrast-enhanced computed tomography (CT) images. The association between visceral adipose tissue and synchronous PM was assessed using univariate and multivariate logistic regression analyses. Results: In the primary cohort, 419 patients were diagnosed with CRC, with 63 presenting with PM. Patients with PM had higher visceral adipose tissue index (VATI) levels compared to those without PM. Additionally, there was a trend towards increased PM incidence with elevated VATI. Multivariate logistic regression analysis confirmed that higher VATI was independently associated with PM. These findings were consistent in the validation cohort. Conclusions: VATI is an independent risk factor for occult synchronous PM in patients with CRC.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.