Evidence map›Paper›PMID 40599859›Full record

ReviewFrontiers in oncology2025

Research progress and molecular mechanism of oridonin in the treatment of malignant melanoma.

Tinghan Deng, Jingping Wu, Hongbin Cheng, Jun Lu

Abstract readReview
In one paragraph

Review in Frontiers in oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Tinghan DengSchool of Clinical Medicine, Chengdu University of Traditional Chinese Medicine, Chengdu, China.
Jingping WuDepartment of Medical Cosmetology, Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu, China.
Hongbin ChengDepartment of Dermatology, the Third Affiliated Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu, China.
Jun LuState Key Laboratory of Southwestern Chinese Medicine Resources, School of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Malignant Melanoma (MM) is a highly invasive and easily metastasizing skin cancer. Although current treatments have made certain progress in targeted therapy and immunotherapy, drug resistance and side effects remain urgent problems to be addressed. Oridonin, an active diterpenoid compound derived from the traditional Chinese medicine herb

Indexed as

angiogenesisanti-tumor mechanismsapoptosisimmune regulationmalignant melanomaoridonin

Identifiers

PMID40599859
PMCPMC12209202

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.